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    CG9578 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 33018, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG9578provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0031094
    Locus tag
    Dmel_CG9578
    See related
    AllianceGenome:FB:FBgn0031094
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG9578
    Summary
    Predicted to enable protein phosphatase activator activity. Predicted to be involved in DNA damage checkpoint signaling and TOR signaling. Predicted to be located in cytoplasm. Predicted to be active in cytosol. Is expressed in organism. Orthologous to human TIPRL (TOR signaling pathway regulator). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG9578 in Genome Data Viewer
    Location:
    19C1-19C1; 1-64 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (20170222..20171526)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (20064255..20065559)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene PHD finger protein 7 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Annexin B10 Neighboring gene Sperm-specific dynein intermediate chain 1 Neighboring gene pseudo

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. TIP41 interacts with TAP42 and negatively regulates the TOR signaling pathway. Jacinto E, et al. Mol Cell, 2001 Nov. PMID 11741537
    2. Microarray analysis of juvenile hormone response in Drosophila melanogaster S2 cells. Willis DK, et al. J Insect Sci, 2010. PMID 20672983, Free PMC Article
    3. Systematic identification of functional orthologs based on protein network comparison. Bandyopadhyay S, et al. Genome Res, 2006 Mar. PMID 16510899, Free PMC Article
    4. Identification of GOLPH3 Partners in Drosophila Unveils Potential Novel Roles in Tumorigenesis and Neural Disorders. Sechi S, et al. Cells, 2021 Sep 6. PMID 34571985, Free PMC Article
    5. Transcriptional regulators form diverse groups with context-dependent regulatory functions. Stampfel G, et al. Nature, 2015 Dec 3. PMID 26550828

    See all (28) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables protein phosphatase activator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in DNA damage checkpoint signaling ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in TOR signaling IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG9578-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      20170222..20171526
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_134533.4 → NP_608377.1  uncharacterized protein Dmel_CG9578 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_608377.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q95TV2, Q9W5W6
      Related
      FBpp0070007
      Conserved Domains (1) summary
      pfam04176
      Location:79 → 236
      TIP41; TIP41-like family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9W5W6 Q9W5W6

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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