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    CG31759 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 326158, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG31759provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0051759
    Locus tag
    Dmel_CG31759
    See related
    AllianceGenome:FB:FBgn0051759
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    3635; BcDNA:AT13596; BcDNA:LD05405; d3635; Dmel\CG31759; ms(2)01284
    Summary
    Predicted to enable 3'-5'-RNA exonuclease activity. Predicted to be involved in nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay. Predicted to be active in mitochondrion. Is expressed in organism. Orthologous to human PDE12 (phosphodiesterase 12). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG31759 in Genome Data Viewer
    Location:
    33D3-33D3; 2-46 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (12207709..12210110)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (12207709..12210110)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR43356 Neighboring gene atilla Neighboring gene crooked Neighboring gene bruno 1 Neighboring gene long non-coding RNA:CR45282 Neighboring gene long non-coding RNA:CR45283

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Subunits of the Drosophila CCR4-NOT complex and their roles in mRNA deadenylation. Temme C, et al. RNA, 2010 Jul. PMID 20504953, Free PMC Article
    2. Deadenylation of mRNA by the CCR4-NOT complex in Drosophila: molecular and developmental aspects. Temme C, et al. Front Genet, 2014. PMID 24904643, Free PMC Article
    3. The complex I subunit NDUFA10 selectively rescues Drosophila pink1 mutants through a mechanism independent of mitophagy. Pogson JH, et al. PLoS Genet, 2014 Nov. PMID 25412178, Free PMC Article
    4. Effect of Larval Nutrition on Maternal mRNA Contribution to the Drosophila Egg. Crofton AE, et al. G3 (Bethesda), 2018 May 31. PMID 29666195, Free PMC Article
    5. Genome-wide association analysis of oxidative stress resistance in Drosophila melanogaster. Weber AL, et al. PLoS One, 2012. PMID 22496853, Free PMC Article

    See all (27) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables 3'-5'-RNA exonuclease activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables catalytic activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in mitochondrial mRNA catabolic process ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in mitochondrial matrix ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG31759-PC
    CG31759-PD
    NP_723735.2
    NP_723736.2

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      12207709..12210110
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_165001.3 → NP_723736.2  uncharacterized protein Dmel_CG31759, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_723736.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      B5RJE2, Q8IP91
      Conserved Domains (1) summary
      cl00490
      Location:239 → 561
      EEP; Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily

    2. NM_165000.2 → NP_723735.2  uncharacterized protein Dmel_CG31759, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_723735.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      B5RJE2, Q8IP91
      Conserved Domains (1) summary
      cl00490
      Location:239 → 561
      EEP; Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8IP91 Q8IP91
    Q8T0G0 Q8T0G0
    Q8T471 Q8T471

    Gene LinkOut

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