U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    stw straw [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 35494, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    stwprovided by FlyBase
    Official Full Name
    strawprovided by FlyBase
    Primary source
    FLYBASE:FBgn0286203
    Locus tag
    Dmel_CG42345
    See related
    AllianceGenome:FB:FBgn0286203
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG10398; CG10408; CG30437; CG32838; CG42345; Dmel\CG42345; laccase2; Laccase2; MCO2; str
    Old locus tag
    Dmel_CG30437; Dmel_CG32838
    Summary
    Predicted to enable catechol oxidase activity and tyrosinase activity. Involved in chitin-based cuticle development. Predicted to be active in plasma membrane. Is expressed in adult head. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See stw in Genome Data Viewer
    Location:
    41F1-41F1; 2-55 cM
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (5413744..5456095)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (1301249..1343600)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR42646 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene UDP-glycosyltransferase family 50 member B3 Neighboring gene Troponin C isoform 4

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. CRISPR/Cas13 effectors have differing extents of off-target effects that limit their utility in eukaryotic cells. Ai Y, et al. Nucleic Acids Res, 2022 Jun 24. PMID 35244715, Free PMC Article
    2. Inducible Expression of Eukaryotic Circular RNAs from Plasmids. Tatomer DC, et al. Methods Mol Biol, 2017. PMID 28766295
    3. Insect multicopper oxidases: diversity, properties, and physiological roles. Dittmer NT, et al. Insect Biochem Mol Biol, 2010 Mar. PMID 20219675
    4. The Effect of Adult Body Color Mutations upon the Larva of Drosophila Melanogaster. Brehme KS. Proc Natl Acad Sci U S A, 1941 Jun 15. PMID 16588454, Free PMC Article
    5. The Beaded Minute combination and sex-determination in Drosophila. Sturtevant AH. Proc Natl Acad Sci U S A, 1949 Jun. PMID 16588895, Free PMC Article

    See all (65) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    mobile_element

    • Loc: 5417206-5417246 mobile_element_type = transposon:1360{}3623
    • Loc: 5421131-5421458 mobile_element_type = transposon:S{}665
    • Loc: 5424322-5424849 mobile_element_type = transposon:INE-1{}3226
    • Loc: 5424947-5424997 mobile_element_type = transposon:F{}3569
    • Loc: 5433449-5433947 mobile_element_type = transposon:INE-1{}3229
    • Loc: 5435080-5435129 mobile_element_type = transposon:INE-1{}3231
    • Loc: 5438373-5438471 mobile_element_type = transposon:Fw2{}3783
    • Loc: 5438666-5439216 mobile_element_type = transposon:INE-1{}3235
    • Loc: 5442603-5444659 mobile_element_type = transposon:Rt1b{}3599
    • Loc: 5444806-5446285 mobile_element_type = transposon:I{}3125
    • Loc: 5453071-5453132 mobile_element_type = transposon:INE-1{}4244

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables catechol oxidase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables copper ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables oxidoreductase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables tyrosinase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in chitin-based cuticle development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in iron ion transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    straw
    Names
    CG42345-PA
    CG42345-PD
    CG42345-PE
    CG42345-PF
    CG42345-PG
    Laccase-2
    Laccase2
    laccase
    laccase 2
    stw-PA
    stw-PD
    stw-PE
    stw-PF
    stw-PG
    NP_001137606.1
    NP_001260709.1
    NP_610170.2
    NP_724412.1
    NP_724413.2

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      5413744..5456095
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_136326.3 → NP_610170.2  straw, isoform E [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_610170.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      A1Z6F4, Q86P50
      Conserved Domains (4) summary
      cd13858
      Location:230 → 333
      CuRO_1_tcLCC2_insect_like; The first cupredoxin domain of insect laccases similar to laccase 2 in Tribolium castaneum
      cd13884
      Location:352 → 500
      CuRO_2_tcLCC_insect_like; The second cupredoxin domain of the insect laccases similar to laccase 2 in Tribolium castaneum
      cd13905
      Location:599 → 767
      CuRO_3_tcLLC2_insect_like; The third cupredoxin domain of the insect laccases similar to laccase 2 in Tribolium castaneum
      TIGR03388
      Location:230 → 775
      ascorbase; L-ascorbate oxidase, plant type

    2. NM_001273780.1 → NP_001260709.1  straw, isoform G [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001260709.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4KF30
      Conserved Domains (4) summary
      cd13858
      Location:230 → 333
      CuRO_1_tcLCC2_insect_like; The first cupredoxin domain of insect laccases similar to laccase 2 in Tribolium castaneum
      cd13884
      Location:352 → 500
      CuRO_2_tcLCC_insect_like; The second cupredoxin domain of the insect laccases similar to laccase 2 in Tribolium castaneum
      cd13905
      Location:599 → 767
      CuRO_3_tcLLC2_insect_like; The third cupredoxin domain of the insect laccases similar to laccase 2 in Tribolium castaneum
      TIGR03388
      Location:230 → 775
      ascorbase; L-ascorbate oxidase, plant type

    3. NM_001144134.2 → NP_001137606.1  straw, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001137606.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      B7YZT1, Q86P50
      Conserved Domains (4) summary
      cd13858
      Location:230 → 333
      CuRO_1_tcLCC2_insect_like; The first cupredoxin domain of insect laccases similar to laccase 2 in Tribolium castaneum
      cd13884
      Location:352 → 500
      CuRO_2_tcLCC_insect_like; The second cupredoxin domain of the insect laccases similar to laccase 2 in Tribolium castaneum
      cd13905
      Location:599 → 767
      CuRO_3_tcLLC2_insect_like; The third cupredoxin domain of the insect laccases similar to laccase 2 in Tribolium castaneum
      TIGR03388
      Location:230 → 756
      ascorbase; L-ascorbate oxidase, plant type

    4. NM_165431.3 → NP_724412.1  straw, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_724412.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7JQF6, Q86P50
      Related
      FBpp0289196
      Conserved Domains (4) summary
      cd13858
      Location:230 → 333
      CuRO_1_tcLCC2_insect_like; The first cupredoxin domain of insect laccases similar to laccase 2 in Tribolium castaneum
      cd13884
      Location:352 → 500
      CuRO_2_tcLCC_insect_like; The second cupredoxin domain of the insect laccases similar to laccase 2 in Tribolium castaneum
      cd13905
      Location:599 → 767
      CuRO_3_tcLLC2_insect_like; The third cupredoxin domain of the insect laccases similar to laccase 2 in Tribolium castaneum
      TIGR03388
      Location:230 → 766
      ascorbase; L-ascorbate oxidase, plant type

    5. NM_165432.3 → NP_724413.2  straw, isoform F [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_724413.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      A1Z6F6, Q86P50
      Conserved Domains (4) summary
      cd13858
      Location:195 → 298
      CuRO_1_tcLCC2_insect_like; The first cupredoxin domain of insect laccases similar to laccase 2 in Tribolium castaneum
      cd13884
      Location:317 → 465
      CuRO_2_tcLCC_insect_like; The second cupredoxin domain of the insect laccases similar to laccase 2 in Tribolium castaneum
      cd13905
      Location:564 → 732
      CuRO_3_tcLLC2_insect_like; The third cupredoxin domain of the insect laccases similar to laccase 2 in Tribolium castaneum
      TIGR03388
      Location:195 → 731
      ascorbase; L-ascorbate oxidase, plant type
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A0A0B4KF30 A0A0B4KF30
    A1Z6F4 A1Z6F4
    A1Z6F6 A1Z6F6
    B7YZT1 B7YZT1
    Q7JQF6 Q7JQF6
    Q86P50 Q86P50

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
    Molecular Biology Databases
    Research Materials
    Tools