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    Swt1 Swt1 RNA endoribonuclease [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 32788, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Swt1provided by FlyBase
    Official Full Name
    Swt1 RNA endoribonucleaseprovided by FlyBase
    Primary source
    FLYBASE:FBgn0030892
    Locus tag
    Dmel_CG7206
    See related
    AllianceGenome:FB:FBgn0030892
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG7206; Dmel\CG7206; DmSwt1
    Summary
    Predicted to enable RNA endonuclease activity. Predicted to be involved in nuclear mRNA surveillance of mRNP export. Is expressed in organism. Orthologous to human SWT1 (SWT1 RNA endoribonuclease homolog). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Swt1 in Genome Data Viewer
    Location:
    16F6-16F6; 1-59 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (18088725..18090509, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (17982758..17984542, complement)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene Dynein heavy chain at 16F Neighboring gene uncharacterized protein Neighboring gene transcriptional Adaptor 3 Neighboring gene Rho GTPase activating protein at 16F Neighboring gene scully

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. An endoribonuclease functionally linked to perinuclear mRNP quality control associates with the nuclear pore complexes. Skruzný M, et al. PLoS Biol, 2009 Jan 6. PMID 19127978, Free PMC Article
    2. Differential gene expression related to Nora virus infection of Drosophila melanogaster. Cordes EJ, et al. Virus Res, 2013 Aug. PMID 23603562, Free PMC Article
    3. Putative synaptic genes defined from a Drosophila whole body developmental transcriptome by a machine learning approach. Pazos Obregón F, et al. BMC Genomics, 2015 Sep 15. PMID 26370122, Free PMC Article
    4. A protein complex network of Drosophila melanogaster. Guruharsha KG, et al. Cell, 2011 Oct 28. PMID 22036573, Free PMC Article
    5. Transient junction anisotropies orient annular cell polarization in the Drosophila airway tubes. Hosono C, et al. Nat Cell Biol, 2015 Dec. PMID 26551273

    See all (27) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables RNA endonuclease activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in nuclear mRNA surveillance of mRNP export ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Swt1 RNA endoribonuclease
    Names
    CG7206-PB
    CG7206-PC
    Swt1-PB
    Swt1-PC

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      18088725..18090509 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_206776.2 → NP_996499.1  Swt1 RNA endoribonuclease, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_996499.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      F3YDM7, Q7KUW4
      Conserved Domains (1) summary
      cd09880
      Location:254 → 392
      PIN_Smg5-Smg6-like; PIN domain

    2. NM_001258799.1 → NP_001245728.1  Swt1 RNA endoribonuclease, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001245728.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      M9NFB4
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    M9NFB4 M9NFB4
    Q7KUW4 Q7KUW4
    Q9VWY9 Q9VWY9

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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