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    CG4313 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 31169, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG4313provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0025632
    Locus tag
    Dmel_CG4313
    See related
    AllianceGenome:FB:FBgn0025632
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG 4313; Dmel\CG4313; Dmel_CG4313; EG:22E5.10
    Summary
    Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in membrane. Is expressed in larval visceral muscle cell and organism. Orthologous to human GPR84 (G protein-coupled receptor 84). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG4313 in Genome Data Viewer
    Location:
    2C7-2C8; 1-0.5 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (2041868..2055414)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (1935901..1949447)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene enhanced adult sensory threshold Neighboring gene alpha actinin Neighboring gene mir-4954 stem loop Neighboring gene ultraspiracle Neighboring gene uncharacterized protein Neighboring gene moody Neighboring gene antisense RNA:CR44896 Neighboring gene Salt-inducible kinase 2 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Investigation of Evolutionary History and Origin of the Tre1 Family Suggests a Role in Regulating Hemocytes Cells Infiltration of the Blood-Brain Barrier. Kubick N, et al. Insects, 2021 Sep 29. PMID 34680651, Free PMC Article
    2. Melatonin increases the regularity of cardiac rhythmicity in the Drosophila heart in both wild-type and strains bearing pathogenic mutations. VanKirk T, et al. J Comp Physiol B, 2017 Jan. PMID 27448293
    3. moody encodes two GPCRs that regulate cocaine behaviors and blood-brain barrier permeability in Drosophila. Bainton RJ, et al. Cell, 2005 Oct 7. PMID 16213219
    4. Tre1, a G protein-coupled receptor, directs transepithelial migration of Drosophila germ cells. Kunwar PS, et al. PLoS Biol, 2003 Dec. PMID 14691551, Free PMC Article
    5. Extensive crosstalk of G protein-coupled receptors with the Hedgehog signalling pathway. Saad F, et al. Development, 2021 Apr 1. PMID 33653875, Free PMC Article

    See all (41) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables G protein-coupled receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables G protein-coupled receptor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in G protein-coupled receptor signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in G protein-coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in G protein-coupled receptor signaling pathway ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG4313-PC
    CG4313-PD
    CG4313-PE

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      2041868..2055414
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001297871.1 → NP_001284800.1  uncharacterized protein Dmel_CG4313, isoform E [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001284800.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8T9K8
      Conserved Domains (1) summary
      cl21561
      Location:248 → 315
      7tm_4; Olfactory receptor

    2. NM_001297870.1 → NP_001284799.1  uncharacterized protein Dmel_CG4313, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001284799.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8T9K8
      Conserved Domains (1) summary
      cl21561
      Location:248 → 315
      7tm_4; Olfactory receptor

    3. NM_130615.3 → NP_569971.3  uncharacterized protein Dmel_CG4313, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_569971.3

      Status: REVIEWED

      UniProtKB/TrEMBL
      O77269, Q9W533
      Conserved Domains (1) summary
      cd15210
      Location:78 → 505
      7tmA_GPR84-like; G protein-coupled receptor 84 and similar proteins, member of the class A family of seven-transmembrane G protein-coupled receptors
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O77269 O77269
    Q8T9K8 Q8T9K8
    Q9W533 Q9W533

    Gene LinkOut

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