U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    JYalpha JYalpha [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 5740846, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    JYalphaprovided by FlyBase
    Official Full Name
    JYalphaprovided by FlyBase
    Primary source
    FLYBASE:FBgn0267363
    Locus tag
    Dmel_CG45760
    See related
    AllianceGenome:FB:FBgn0267363
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG17923; CG40625; CG45760; Dmel\CG45760; JY-alpha; Jyalpha; JYAlpha
    Old locus tag
    Dmel_CG17923; Dmel_CG40625
    Summary
    Predicted to enable P-type sodium:potassium-exchanging transporter activity. Involved in flagellated sperm motility. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in adult head. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See JYalpha in Genome Data Viewer
    Location:
    101F1-101F1; 4-0 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 4 NC_004353.4 (879..5039)

    Chromosome 4 - NC_004353.4Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene pseudo

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_004353.4 Chromosome 4 Reference Release 6 plus ISO1 MT Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Proteomic changes in response to crystal formation in Drosophila Malpighian tubules. Chung VY, et al. Fly (Austin), 2016 Apr 2. PMID 27064297, Free PMC Article
    2. The molecular evolutionary basis of species formation. Presgraves DC. Nat Rev Genet, 2010 Mar. PMID 20051985
    3. Multiple SET methyltransferases are required to maintain normal heterochromatin domains in the genome of Drosophila melanogaster. Brower-Toland B, et al. Genetics, 2009 Apr. PMID 19189944, Free PMC Article
    4. Evolution of a distinct genomic domain in Drosophila: comparative analysis of the dot chromosome in Drosophila melanogaster and Drosophila virilis. Leung W, et al. Genetics, 2010 Aug. PMID 20479145, Free PMC Article
    5. Chromatin evolution and molecular drive in speciation. Sawamura K. Int J Evol Biol, 2012. PMID 22191063, Free PMC Article

    See all (34) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    • Annotated by Drosophila Heterochromatin Genome Project, Lawrence Berkeley National Lab, http://www.dhgp.org

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables P-type potassium transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables P-type sodium:potassium-exchanging transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables P-type sodium:potassium-exchanging transporter activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in flagellated sperm motility IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in intracellular potassium ion homeostasis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in intracellular sodium ion homeostasis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in monoatomic cation transport ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in potassium ion import across plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in potassium ion transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in proton transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in sodium ion export across plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    JYalpha
    Names
    CG45760-PB
    JYalpha-PB
    NP_001104092.2

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004353.4 Reference assembly

      Range
      879..5039
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001110622.3 → NP_001104092.2  JYalpha [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001104092.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      A8QI34, Q9U458
      Conserved Domains (6) summary
      smart00831
      Location:29 → 102
      Cation_ATPase_N; Cation transporter/ATPase, N-terminus
      COG4087
      Location:673 → 738
      COG4087; Soluble P-type ATPase [General function prediction only]
      TIGR01106
      Location:17 → 1009
      ATPase-IIC_X-K; sodium or proton efflux -- potassium uptake antiporter, P-type ATPase, alpha subunit
      pfam00122
      Location:123 → 354
      E1-E2_ATPase; E1-E2 ATPase
      pfam00689
      Location:785 → 994
      Cation_ATPase_C; Cation transporting ATPase, C-terminus
      pfam13246
      Location:416 → 509
      Cation_ATPase; Cation transport ATPase (P-type)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A8QI34 A8QI34
    Q9U458 Q9U458

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools