ATPsynepsilonL ATP synthase, epsilon subunit-like [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: ATPsynepsilonLprovided by FlyBase
Official Full Name: ATP synthase, epsilon subunit-likeprovided by FlyBase
Primary source: FLYBASE:FBgn0051477
Locus tag: Dmel_CG31477
See related: AllianceGenome:FB:FBgn0051477
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: ATPE; CG12810; CG31477; Dmel\CG31477
Summary: Predicted to contribute to proton-transporting ATP synthase activity, rotational mechanism. Predicted to be involved in proton motive force-driven mitochondrial ATP synthesis and proton transmembrane transport. Predicted to be part of proton-transporting ATP synthase, central stalk. Predicted to be active in mitochondrial inner membrane. Is expressed in adult head. Human ortholog(s) of this gene implicated in mitochondrial complex V (ATP synthase) deficiency nuclear type 3. Orthologous to human ATP5F1E (ATP synthase F1 subunit epsilon) and ATP5F1EP2 (ATP synthase F1 subunit epsilon pseudogene 2). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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See ATPsynepsilonL in Genome Data Viewer

Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	3R	NT_033777.3 (10121773..10122320)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	3R	NT_033777.2 (5947495..5948042)

Chromosome 3R - NT_033777.3 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
contributes_to proton-transporting ATP synthase activity, rotational mechanism	IBA Inferred from Biological aspect of Ancestor more info
enables proton-transporting ATP synthase activity, rotational mechanism	IEA Inferred from Electronic Annotation more info
contributes_to proton-transporting ATP synthase activity, rotational mechanism	ISS Inferred from Sequence or Structural Similarity more info

Process	Evidence Code	Pubs
involved_in proton motive force-driven ATP synthesis	IEA Inferred from Electronic Annotation more info
involved_in proton motive force-driven ATP synthesis	ISS Inferred from Sequence or Structural Similarity more info
involved_in proton motive force-driven mitochondrial ATP synthesis	IBA Inferred from Biological aspect of Ancestor more info
involved_in proton transmembrane transport	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
is_active_in mitochondrial inner membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in mitochondrial inner membrane	IEA Inferred from Electronic Annotation more info
part_of proton-transporting ATP synthase complex, catalytic core F(1)	IEA Inferred from Electronic Annotation more info
part_of proton-transporting ATP synthase complex, catalytic core F(1)	ISS Inferred from Sequence or Structural Similarity more info
part_of proton-transporting ATP synthase, central stalk	ISS Inferred from Sequence or Structural Similarity more info

Names: ATP synthase epsilon chain; ATPsynepsilonL-PA; ATPsynepsilonL-PB; ATPsynepsilonL-PC; CG31477-PA; CG31477-PB; CG31477-PC

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