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    rdo reduced ocelli [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 35077, updated on 9-Dec-2024

    Summary

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    Official Symbol
    rdoprovided by FlyBase
    Official Full Name
    reduced ocelliprovided by FlyBase
    Primary source
    FLYBASE:FBgn0243486
    Locus tag
    Dmel_CG15151
    See related
    AllianceGenome:FB:FBgn0243486
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG15151; CT35050; Dmel\CG15151; PFE; Rdo
    Summary
    Involved in epithelium regeneration; ocellus development; and regulation of stem cell division. Is expressed in several structures, including adult head; embryonic brain; embryonic ventral epidermis; epithelium; and eye. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See rdo in Genome Data Viewer
    Location:
    36E3-36E3; 2-53 cM
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (18012380..18070246)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (18012380..18070246)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene elfless Neighboring gene Arrestin 1 Neighboring gene neither inactivation nor afterpotential D

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Mutations affecting phenol oxidase activity in Drosophila: quicksilver and tyrosinase-1. Pentz ES, et al. Biochem Genet, 1990 Apr. PMID 2116788
    2. Visualization of binding patterns for five Leucine-rich repeat proteins in the Drosophila embryo. Bali N, et al. MicroPubl Biol, 2019 Dec 18. PMID 32550403, Free PMC Article
    3. The retrograde IFT dynein is required for normal function of diverse mechanosensory cilia in Drosophila. Sharma Y, et al. Front Mol Neurosci, 2023. PMID 37808471, Free PMC Article
    4. Ultrastructure of the ocellar visual system in normal and mutant Drosophila melanogaster. Stark WS, et al. J Neurogenet, 1989 May. PMID 2500507
    5. reduced ocelli encodes the leucine rich repeat protein Pray For Elves in Drosophila melanogaster. Caldwell JC, et al. Fly (Austin), 2007 May-Jun. PMID 18820435, Free PMC Article

    See all (52) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The PFE locus maps to polytene region 36E on chromosome 2L between elfless (Fbgn0032660) and Arrestin 1 (Fbgn0000120).
      Title: reduced ocelli encodes the leucine rich repeat protein Pray For Elves in Drosophila melanogaster.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    mobile_element

    • Loc: 18051931-18061019 mobile_element_type = transposon:roo{}402

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in epithelium regeneration IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in ocellus development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of stem cell division IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    reduced ocelli
    Names
    CG15151-PA
    CG15151-PB
    pray For elves
    rdo-PA
    rdo-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      18012380..18070246
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001299095.1 → NP_001286024.1  reduced ocelli, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001286024.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      X2J6K6
      Conserved Domains (4) summary
      cd00116
      Location:151 → 422
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
      sd00033
      Location:108 → 131
      LRR_RI; leucine-rich repeat [structural motif]
      pfam12799
      Location:298 → 342
      LRR_4; Leucine Rich repeats (2 copies)
      pfam13855
      Location:274 → 334
      LRR_8; Leucine rich repeat

    2. NM_136017.3 → NP_609861.1  reduced ocelli, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_609861.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VJA9
      Related
      FBpp0080582
      Conserved Domains (3) summary
      cd00116
      Location:151 → 406
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
      sd00033
      Location:108 → 131
      LRR_RI; leucine-rich repeat [structural motif]
      pfam13855
      Location:274 → 334
      LRR_8; Leucine rich repeat
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VJA9 Q9VJA9
    X2J6K6 X2J6K6

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