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    Ugt50B3 UDP-glycosyltransferase family 50 member B3 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 246614, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Ugt50B3provided by FlyBase
    Official Full Name
    UDP-glycosyltransferase family 50 member B3provided by FlyBase
    Primary source
    FLYBASE:FBgn0050438
    Locus tag
    Dmel_CG30438
    See related
    AllianceGenome:FB:FBgn0050438
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:LD09936; BcDNA:RE54684; CG30438; Dmel\CG30438; UGT50B3
    Summary
    Predicted to enable UDP-glycosyltransferase activity. Predicted to be involved in glycosylation. Predicted to be active in endoplasmic reticulum membrane. Is expressed in several structures, including adult head; embryonic head epidermis; embryonic ventral epidermis; epithelium; and plasmatocyte primordium. Orthologous to several human genes including UGT1A8 (UDP glucuronosyltransferase family 1 member A8); UGT2A3 (UDP glucuronosyltransferase family 2 member A3); and UGT2B10 (UDP glucuronosyltransferase family 2 member B10). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Ugt50B3 in Genome Data Viewer
    Location:
    41F2-41F3; 2-55 cM
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (5496674..5549543)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (1384179..1437048)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene straw Neighboring gene uncharacterized protein Neighboring gene Troponin C isoform 4 Neighboring gene uncharacterized protein Neighboring gene Fission, mitochondrial 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Sex-dependent gene expression and evolution of the Drosophila transcriptome. Ranz JM, et al. Science, 2003 Jun 13. PMID 12805547
    2. Natural selection shapes genome-wide patterns of copy-number polymorphism in Drosophila melanogaster. Emerson JJ, et al. Science, 2008 Jun 20. PMID 18535209
    3. Molecular landscape of modified histones in Drosophila heterochromatic genes and euchromatin-heterochromatin transition zones. Yasuhara JC, et al. PLoS Genet, 2008 Jan. PMID 18208336, Free PMC Article
    4. The UDP-Glycosyltransferase Family in Drosophila melanogaster: Nomenclature Update, Gene Expression and Phylogenetic Analysis. Ahn SJ, et al. Front Physiol, 2021. PMID 33815151, Free PMC Article
    5. Unlimited Genetic Switches for Cell-Type-Specific Manipulation. Garcia-Marques J, et al. Neuron, 2019 Oct 23. PMID 31395429

    See all (43) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    mobile_element

    • Loc: 5497841-5498439 mobile_element_type = transposon:INE-1{}4259
    • Loc: 5501411-5502906 mobile_element_type = transposon:Tc1-2{}4466
    • Loc: 5504404-5504452 mobile_element_type = transposon:INE-1{}4262
    • Loc: 5508596-5508725 mobile_element_type = transposon:INE-1{}4265
    • Loc: 5509424-5509685 mobile_element_type = transposon:INE-1{}4266
    • Loc: 5510996-5514782 mobile_element_type = transposon:HB{}673
    • Loc: 5516434-5516521 mobile_element_type = transposon:Rt1c{}4964
    • Loc: 5516565-5516846 mobile_element_type = transposon:1360{}4373
    • Loc: 5516942-5518716 mobile_element_type = transposon:INE-1{}4271
    • Loc: 5520057-5520382 mobile_element_type = transposon:INE-1{}4275
    • Loc: 5521172-5521613 mobile_element_type = transposon:HB{}674
    • Loc: 5521650-5521724 mobile_element_type = transposon:INE-1{}4278
    • Loc: 5529323-5529350 mobile_element_type = transposon:INE-1{}4285
    • Loc: 5529611-5529959 mobile_element_type = transposon:Tc1-2{}4469
    • Loc: 5532444-5536059 mobile_element_type = transposon:Doc4{}4397
    • Loc: 5533960-5534579 mobile_element_type = transposon:gypsy8{}5023
    • Loc: 5535242-5535482 mobile_element_type = transposon:Doc{}4338
    • Loc: 5536175-5536245 mobile_element_type = transposon:Doc{}4340
    • Loc: 5540832-5541001 mobile_element_type = transposon:INE-1{}4299
    • Loc: 5543245-5547271 mobile_element_type = transposon:invader1{}677

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables UDP-glycosyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables UDP-glycosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables UDP-glycosyltransferase activity ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in glycosylation ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in endoplasmic reticulum membrane ISM
    Inferred from Sequence Model
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    UDP-glycosyltransferase family 50 member B3
    Names
    CG30438-PA
    CG30438-PB
    CG30438-PC
    CG30438-PD
    CG30438-PE
    Ugt50B3-PA
    Ugt50B3-PB
    Ugt50B3-PC
    Ugt50B3-PD
    Ugt50B3-PE

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      5496674..5549543
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_165436.3 → NP_724417.3  UDP-glycosyltransferase family 50 member B3, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_724417.3

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8SYL7
      Related
      FBpp0085404
      Conserved Domains (2) summary
      PHA03392
      Location:172 → 479
      egt; ecdysteroid UDP-glucosyltransferase; Provisional
      COG1819
      Location:28 → 434
      YjiC; UDP:flavonoid glycosyltransferase YjiC, YdhE family [Carbohydrate transport and metabolism]

    2. NM_165435.3 → NP_724416.2  UDP-glycosyltransferase family 50 member B3, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_724416.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7K142
      Related
      FBpp0085403
      Conserved Domains (1) summary
      PHA03392
      Location:83 → 390
      egt; ecdysteroid UDP-glucosyltransferase; Provisional

    3. NM_165437.3 → NP_724418.3  UDP-glycosyltransferase family 50 member B3, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_724418.3

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8SYL7
      Related
      FBpp0085405
      Conserved Domains (2) summary
      PHA03392
      Location:172 → 479
      egt; ecdysteroid UDP-glucosyltransferase; Provisional
      COG1819
      Location:28 → 434
      YjiC; UDP:flavonoid glycosyltransferase YjiC, YdhE family [Carbohydrate transport and metabolism]

    4. NM_165438.3 → NP_724419.3  UDP-glycosyltransferase family 50 member B3, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_724419.3

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8SYL7
      Related
      FBpp0085406
      Conserved Domains (2) summary
      PHA03392
      Location:172 → 479
      egt; ecdysteroid UDP-glucosyltransferase; Provisional
      COG1819
      Location:28 → 434
      YjiC; UDP:flavonoid glycosyltransferase YjiC, YdhE family [Carbohydrate transport and metabolism]

    5. NM_001273781.1 → NP_001260710.1  UDP-glycosyltransferase family 50 member B3, isoform E [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001260710.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8SYL7
      Conserved Domains (2) summary
      PHA03392
      Location:172 → 479
      egt; ecdysteroid UDP-glucosyltransferase; Provisional
      COG1819
      Location:28 → 434
      YjiC; UDP:flavonoid glycosyltransferase YjiC, YdhE family [Carbohydrate transport and metabolism]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q7K142 Q7K142
    Q8SYL7 Q8SYL7

    Gene LinkOut

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