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    fd19B forkhead domain 19B [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 33010, updated on 9-Dec-2024

    Summary

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    Official Symbol
    fd19Bprovided by FlyBase
    Official Full Name
    forkhead domain 19Bprovided by FlyBase
    Primary source
    FLYBASE:FBgn0031086
    Locus tag
    Dmel_CG9571
    See related
    AllianceGenome:FB:FBgn0031086
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG9571; Dmcg9571; Dmel\CG9571; FoxG
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in anatomical structure morphogenesis; cell differentiation; and regulation of transcription by RNA polymerase II. Is expressed in several structures, including anlage in statu nascendi; anterior endoderm anlage; central brain anlage in statu nascendi; foregut anlage in statu nascendi; and head mesoderm anlage. Orthologous to human FOXI3 (forkhead box I3); FOXJ2 (forkhead box J2); and FOXS1 (forkhead box S1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See fd19B in Genome Data Viewer
    Location:
    19B1-19B1; 1-64 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (20091428..20092408, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (19985461..19986441, complement)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene Dopamine 2-like receptor Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR45628 Neighboring gene uncharacterized protein Neighboring gene Odorant receptor 19b

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Association of orthodenticle with natural variation for early embryonic patterning in Drosophila melanogaster. Goering LM, et al. J Exp Zool B Mol Dev Evol, 2009 Dec 15. PMID 19488993, Free PMC Article
    2. The role of binding site cluster strength in Bicoid-dependent patterning in Drosophila. Ochoa-Espinosa A, et al. Proc Natl Acad Sci U S A, 2005 Apr 5. PMID 15793007, Free PMC Article
    3. Evolutionary origins of transcription factor binding site clusters. He X, et al. Mol Biol Evol, 2012 Mar. PMID 22075113, Free PMC Article
    4. Phylogenetic relationships of the Fox (Forkhead) gene family in the Bilateria. Mazet F, et al. Gene, 2003 Oct 16. PMID 14563554
    5. Survey of forkhead domain encoding genes in the Drosophila genome: Classification and embryonic expression patterns. Lee HH, et al. Dev Dyn, 2004 Feb. PMID 14745961

    See all (38) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in anatomical structure morphogenesis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in cell differentiation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    forkhead domain 19B
    Names
    CG9571-PA
    fd19B-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      20091428..20092408 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_134525.2 → NP_608369.1  forkhead domain 19B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_608369.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q0IGQ1, Q9W5X5
      Related
      FBpp0070031
      Conserved Domains (1) summary
      cd00059
      Location:58 → 135
      FH; Forkhead (FH), also known as a "winged helix". FH is named for the Drosophila fork head protein, a transcription factor which promotes terminal rather than segmental development. This family of transcription factor domains, which bind to B-DNA as ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9W5X5 Q9W5X5

    Gene LinkOut

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