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    CG3939 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 31295, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG3939provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0040396
    Locus tag
    Dmel_CG3939
    See related
    AllianceGenome:FB:FBgn0040396
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BEST:SD07039; Dmel\CG3939; EG:140G11.5
    Summary
    Predicted to enable protein-disulfide reductase (NAD(P)H) activity. Predicted to be active in cytosol. Is expressed in embryonic midgut chamber; embryonic small intestine; embryonic/larval midgut; organism; and spermatozoon. Orthologous to human TXNDC17 (thioredoxin domain containing 17). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG3939 in Genome Data Viewer
    Location:
    3C9-3C9; 1-2 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (3175018..3176223)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (3069051..3070256)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Follicle cell protein 3C Neighboring gene dunce Neighboring gene uncharacterized protein Neighboring gene new glue 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The clot gene of Drosophila melanogaster encodes a conserved member of the thioredoxin-like protein superfamily. Giordano E, et al. Mol Genet Genomics, 2003 Feb. PMID 12589444
    2. Multiple signatures of positive selection downstream of notch on the X chromosome in Drosophila melanogaster. DuMont VB, et al. Genetics, 2005 Oct. PMID 16020794, Free PMC Article
    3. Patterns of sequence variability and divergence at the diminutive gene region of Drosophila melanogaster: complex patterns suggest an ancestral selective sweep. Jensen JD, et al. Genetics, 2007 Oct. PMID 17720938, Free PMC Article
    4. Polycomb mediates Myc autorepression and its transcriptional control of many loci in Drosophila. Goodliffe JM, et al. Genes Dev, 2005 Dec 15. PMID 16357214, Free PMC Article
    5. High-resolution mapping of heterochromatin redistribution in a Drosophila position-effect variegation model. Vogel MJ, et al. Epigenetics Chromatin, 2009 Jan 29. PMID 19178722, Free PMC Article

    See all (33) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables protein-disulfide reductase (NAD(P)H) activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables protein-disulfide reductase (NAD(P)H) activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein-disulfide reductase (NAD(P)H) activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG3939-PA
    CG3939-PB
    NP_001284837.1
    NP_570048.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      3175018..3176223
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_130692.4 → NP_570048.1  uncharacterized protein Dmel_CG3939, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_570048.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q32UV4, Q9U1K7, Q9W4T7
      Related
      FBpp0070484
      Conserved Domains (1) summary
      pfam06110
      Location:6 → 124
      DUF953; Eukaryotic protein of unknown function (DUF953)

    2. NM_001297908.1 → NP_001284837.1  uncharacterized protein Dmel_CG3939, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001284837.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q32UV4, Q9U1K7, Q9W4T7
      Conserved Domains (1) summary
      pfam06110
      Location:6 → 124
      DUF953; Eukaryotic protein of unknown function (DUF953)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9U1K7 Q9U1K7

    Gene LinkOut

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