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    CG10011 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 43387, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG10011provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0039590
    Locus tag
    Dmel_CG10011
    See related
    AllianceGenome:FB:FBgn0039590
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG10011
    Summary
    Orthologous to human ANKRD50 (ankyrin repeat domain containing 50). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG10011 in Genome Data Viewer
    Location:
    98D6-98D7; 3-96 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (28607939..28635099, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (24433661..24460821, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Heterogeneous nuclear ribonucleoprotein at 98DE Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene pseudo Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The RRM domain in GW182 proteins contributes to miRNA-mediated gene silencing. Eulalio A, et al. Nucleic Acids Res, 2009 May. PMID 19295135, Free PMC Article
    2. A C-terminal silencing domain in GW182 is essential for miRNA function. Eulalio A, et al. RNA, 2009 Jun. PMID 19383769, Free PMC Article
    3. miR-190 Enhances HIF-Dependent Responses to Hypoxia in Drosophila by Inhibiting the Prolyl-4-hydroxylase Fatiga. De Lella Ezcurra AL, et al. PLoS Genet, 2016 May. PMID 27223464, Free PMC Article
    4. GW182 interaction with Argonaute is essential for miRNA-mediated translational repression and mRNA decay. Eulalio A, et al. Nat Struct Mol Biol, 2008 Apr. PMID 18345015
    5. Deadenylation is a widespread effect of miRNA regulation. Eulalio A, et al. RNA, 2009 Jan. PMID 19029310, Free PMC Article

    See all (37) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG10011-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      28607939..28635099 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_143367.3 → NP_651624.2  uncharacterized protein Dmel_CG10011 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_651624.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8T9G9, Q9VAU5
      Related
      FBpp0084688
      Conserved Domains (7) summary
      smart00382
      Location:344 → 457
      AAA; ATPases associated with a variety of cellular activities
      cd00204
      Location:1479 → 1604
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      pfam01420
      Location:772 → 885
      Methylase_S; Type I restriction modification DNA specificity domain
      pfam12796
      Location:1275 → 1380
      Ank_2; Ankyrin repeats (3 copies)
      pfam13637
      Location:1237 → 1291
      Ank_4; Ankyrin repeats (many copies)
      pfam13857
      Location:1438 → 1489
      Ank_5; Ankyrin repeats (many copies)
      sd00045
      Location:1270 → 1313
      ANK; ANK repeat [structural motif]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8T4F8 Q8T4F8
    Q8T9G9 Q8T9G9
    Q9VAU5 Q9VAU5

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