bnk bottleneck [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: bnkprovided by FlyBase
Official Full Name: bottleneckprovided by FlyBase
Primary source: FLYBASE:FBgn0004389
Locus tag: Dmel_CG1480
See related: AllianceGenome:FB:FBgn0004389
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: Bnk; CG1480; Dmel\CG1480
Summary: Enables actin filament binding activity; phosphatidylinositol-3,4,5-trisphosphate binding activity; and phosphatidylinositol-4,5-bisphosphate binding activity. Involved in actin filament bundle assembly; regulation of embryonic cell shape; and syncytial embryo cellularization. Located in actin filament. Colocalizes with stress fiber. Is expressed in furrow canal and organism. [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	3R	NT_033777.3 (31193362..31194389)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	3R	NT_033777.2 (27019084..27020111)

Chromosome 3R - NT_033777.3 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Submit: New GeneRIF Correction

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables actin filament binding	IDA Inferred from Direct Assay more info	PubMed
enables phosphatidylinositol-3,4,5-trisphosphate binding	IDA Inferred from Direct Assay more info	PubMed
enables phosphatidylinositol-4,5-bisphosphate binding	IDA Inferred from Direct Assay more info	PubMed

Process	Evidence Code	Pubs
involved_in actin filament bundle assembly	IDA Inferred from Direct Assay more info	PubMed
involved_in actin filament bundle organization	IDA Inferred from Direct Assay more info	PubMed
involved_in actin filament organization	TAS Traceable Author Statement more info	PubMed
involved_in regulation of embryonic cell shape	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in syncytial embryo cellularization	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in actin filament	IDA Inferred from Direct Assay more info	PubMed
located_in actin filament	NAS Non-traceable Author Statement more info	PubMed
colocalizes_with stress fiber	IDA Inferred from Direct Assay more info	PubMed