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    Muc14A Mucin 14A [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 318097, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Muc14Aprovided by FlyBase
    Official Full Name
    Mucin 14Aprovided by FlyBase
    Primary source
    FLYBASE:FBgn0052580
    Locus tag
    Dmel_CG32580
    See related
    AllianceGenome:FB:FBgn0052580
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG32580; Dmel\CG32580; muc14a
    Summary
    Predicted to be an extracellular matrix structural constituent. Predicted to be located in extracellular matrix. Is expressed in embryonic/larval salivary gland and spermatozoon. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Muc14A in Genome Data Viewer
    Location:
    14A6-14A6; 1-52 cM
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (16009114..16061722)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (15903147..15955755)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene vacuolar peduncle Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene defective proboscis extension response 18

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A docked mutation phenocopies dumpy oblique alleles via altered vesicle trafficking. Kandasamy S, et al. PeerJ, 2021. PMID 34721959, Free PMC Article
    2. A fly model establishes distinct mechanisms for synthetic CRISPR/Cas9 sex distorters. Fasulo B, et al. PLoS Genet, 2020 Mar. PMID 32168334, Free PMC Article
    3. Complexities of recapitulating polygenic effects in natural populations: replication of genetic effects on wing shape in artificially selected and wild-caught populations of Drosophila melanogaster. Pelletier K, et al. Genetics, 2023 Jul 6. PMID 36961731, Free PMC Article
    4. A potential role for Drosophila mucins in development and physiology. Syed ZA, et al. PLoS One, 2008 Aug 22. PMID 18725942, Free PMC Article
    5. Evi5 promotes collective cell migration through its Rab-GAP activity. Laflamme C, et al. J Cell Biol, 2012 Jul 9. PMID 22778279, Free PMC Article

    See all (25) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables extracellular matrix structural constituent ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular matrix ISM
    Inferred from Sequence Model
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    mucin 14A
    Names
    CG32580-PA
    Muc14A-PA
    Mucin14A

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      16009114..16061722
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_167482.4 → NP_727928.3  mucin 14A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_727928.3

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8IR22
      Related
      FBpp0073985
      Conserved Domains (2) summary
      PRK08581
      Location:11922 → 12215
      PRK08581; N-acetylmuramoyl-L-alanine amidase; Validated
      PRK14949
      Location:14663 → 15055
      PRK14949; DNA polymerase III subunits gamma and tau; Provisional
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8IR22 Q8IR22

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