mRpL44 mitochondrial ribosomal protein L44 [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: mRpL44provided by FlyBase
Official Full Name: mitochondrial ribosomal protein L44provided by FlyBase
Primary source: FLYBASE:FBgn0037330
Locus tag: Dmel_CG2109
See related: AllianceGenome:FB:FBgn0037330
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: CG2109; Dmel\CG2109; MRP-L44
Summary: Predicted to be a structural constituent of ribosome. Predicted to be involved in mitochondrial translational elongation. Predicted to be part of mitochondrial large ribosomal subunit. Predicted to be active in nucleus. Is expressed in several structures, including adult head; adult heart; embryonic/larval midgut; and embryonic/larval midgut primordium. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 16. Orthologous to human MRPL44 (mitochondrial ribosomal protein L44). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	3R	NT_033777.3 (5469463..5470636, complement)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	3R	NT_033777.2 (1295185..1296358, complement)

Chromosome 3R - NT_033777.3 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables double-stranded RNA binding	IEA Inferred from Electronic Annotation more info
NOT enables ribonuclease III activity	ISS Inferred from Sequence or Structural Similarity more info
enables structural constituent of ribosome	TAS Traceable Author Statement more info	PubMed

Process	Evidence Code	Pubs
involved_in RNA processing	IEA Inferred from Electronic Annotation more info
involved_in mitochondrial translation	TAS Traceable Author Statement more info	PubMed
involved_in mitochondrial translational elongation	IBA Inferred from Biological aspect of Ancestor more info
involved_in mitochondrial translational elongation	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
part_of mitochondrial large ribosomal subunit	IBA Inferred from Biological aspect of Ancestor more info
part_of mitochondrial large ribosomal subunit	ISS Inferred from Sequence or Structural Similarity more info	PubMed
part_of mitochondrial large ribosomal subunit	TAS Traceable Author Statement more info	PubMed
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info

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The following sections contain reference sequences that belong to a specific genome build. Explain