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    rdog red dog mine [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 43450, updated on 9-Dec-2024

    Summary

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    Official Symbol
    rdogprovided by FlyBase
    Official Full Name
    red dog mineprovided by FlyBase
    Primary source
    FLYBASE:FBgn0039644
    Locus tag
    Dmel_CG11897
    See related
    AllianceGenome:FB:FBgn0039644
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG11897; DmCG11897; Dmel\CG11897
    Summary
    Predicted to enable ATPase-coupled transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be active in membrane. Is expressed in several structures, including adult head; gland; gut section; imaginal disc; and nephrocyte. Orthologous to human ABCC4 (ATP binding cassette subfamily C member 4 (PEL blood group)). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See rdog in Genome Data Viewer
    Location:
    98F13-98F13; 3-97 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (29158122..29164966)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (24983844..24990688)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Stem-loop binding protein Neighboring gene Regulatory particle non-ATPase 2 Neighboring gene uncharacterized protein Neighboring gene julius seizure Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. julius seizure, a Drosophila Mutant, Defines a Neuronal Population Underlying Epileptogenesis. Horne M, et al. Genetics, 2017 Mar. PMID 28082408, Free PMC Article
    2. Evolutionary conservation of vertebrate blood-brain barrier chemoprotective mechanisms in Drosophila. Mayer F, et al. J Neurosci, 2009 Mar 18. PMID 19295159, Free PMC Article
    3. Canalization of gene expression is a major signature of regulatory cold adaptation in temperate Drosophila melanogaster. von Heckel K, et al. BMC Genomics, 2016 Aug 8. PMID 27502401, Free PMC Article
    4. Identification and characterization of a heme exporter from the MRP family in Drosophila melanogaster. Wang Z, et al. BMC Biol, 2022 Jun 2. PMID 35655259, Free PMC Article
    5. Characterization of a novel pesticide transporter and P-glycoprotein orthologues in Drosophila melanogaster. Denecke S, et al. Proc Biol Sci, 2022 May 25. PMID 35582794, Free PMC Article

    See all (43) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables ABC-type transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATPase-coupled transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    red dog mine
    Names
    CG11897-PA
    CG11897-PB
    rdog-PA
    rdog-PB
    NP_651678.1
    NP_733278.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      29158122..29164966
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_143421.3 → NP_651678.1  red dog mine, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_651678.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q961D3, Q9VAN5
      Related
      FBpp0084756
      Conserved Domains (4) summary
      cd03244
      Location:1096 → 1315
      ABCC_MRP_domain2; ATP-binding cassette domain 2 of multidrug resistance-associated protein
      cd03250
      Location:448 → 650
      ABCC_MRP_domain1; ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C
      TIGR01271
      Location:12 → 1343
      CFTR_protein; cystic fibrosis transmembrane conductor regulator (CFTR)
      cl00549
      Location:821 → 1046
      ABC_membrane; ABC transporter transmembrane region

    2. NM_170399.2 → NP_733278.1  red dog mine, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_733278.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q961D3, Q9VAN5
      Related
      FBpp0084755
      Conserved Domains (4) summary
      cd03244
      Location:1096 → 1315
      ABCC_MRP_domain2; ATP-binding cassette domain 2 of multidrug resistance-associated protein
      cd03250
      Location:448 → 650
      ABCC_MRP_domain1; ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C
      TIGR01271
      Location:12 → 1343
      CFTR_protein; cystic fibrosis transmembrane conductor regulator (CFTR)
      cl00549
      Location:821 → 1046
      ABC_membrane; ABC transporter transmembrane region
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q961D3 Q961D3

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