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    CG17124 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 34485, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG17124provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0032297
    Locus tag
    Dmel_CG17124
    See related
    AllianceGenome:FB:FBgn0032297
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    anon-WO0118547.153; Dmel\CG17124
    Summary
    Predicted to enable protein serine/threonine phosphatase inhibitor activity. Predicted to be located in cytoplasm. Is expressed in several structures, including embryonic brain; gut section; larval muscle cell; sensory nervous system primordium; and visceral mesoderm derivative. Orthologous to several human genes including PPP1R14B (protein phosphatase 1 regulatory inhibitor subunit 14B). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG17124 in Genome Data Viewer
    Location:
    32A5-32A5; 2-43 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (10744075..10756325, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (10744075..10756325, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene mir-4970 stem loop Neighboring gene mir-9378 stem loop Neighboring gene uncharacterized protein Neighboring gene Ubiquitin conjugating enzyme 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Specific requirement of NMDA receptors for long-term memory consolidation in Drosophila ellipsoid body. Wu CL, et al. Nat Neurosci, 2007 Dec. PMID 17982450, Free PMC Article
    2. KEPI, a PKC-dependent protein phosphatase 1 inhibitor regulated by morphine. Liu QR, et al. J Biol Chem, 2002 Apr 12. PMID 11812771
    3. Comparative transcriptional profiling identifies takeout as a gene that regulates life span. Bauer J, et al. Aging (Albany NY), 2010 May. PMID 20519778, Free PMC Article
    4. Identification of downstream targets of the bone morphogenetic protein pathway in the Drosophila nervous system. Kim NC, et al. Dev Dyn, 2010 Sep. PMID 20652954
    5. During Drosophila disc regeneration, JAK/STAT coordinates cell proliferation with Dilp8-mediated developmental delay. Katsuyama T, et al. Proc Natl Acad Sci U S A, 2015 May 5. PMID 25902518, Free PMC Article

    See all (41) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables protein serine/threonine phosphatase inhibitor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG17124-PA
    CG17124-PB
    CG17124-PC

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      10744075..10756325 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_164942.2 → NP_723615.1  uncharacterized protein Dmel_CG17124, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_723615.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VKQ5
      Related
      FBpp0079707
      Conserved Domains (1) summary
      pfam05361
      Location:9 → 124
      PP1_inhibitor; PKC-activated protein phosphatase-1 inhibitor

    2. NM_001298884.1 → NP_001285813.1  uncharacterized protein Dmel_CG17124, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001285813.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VKQ5
      Conserved Domains (1) summary
      pfam05361
      Location:9 → 124
      PP1_inhibitor; PKC-activated protein phosphatase-1 inhibitor

    3. NM_135606.3 → NP_609450.1  uncharacterized protein Dmel_CG17124, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_609450.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VKQ5
      Related
      FBpp0079706
      Conserved Domains (1) summary
      pfam05361
      Location:9 → 124
      PP1_inhibitor; PKC-activated protein phosphatase-1 inhibitor
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VKQ5 Q9VKQ5

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