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    CG30284 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 246527, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG30284provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0050284
    Locus tag
    Dmel_CG30284
    See related
    AllianceGenome:FB:FBgn0050284
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:AT12437; BcDNA:AT22714; Dmel\CG30284; NEST:bs16b04
    Summary
    Predicted to enable sterol binding activity and sterol transfer activity. Predicted to be involved in intracellular sterol transport. Predicted to be active in endoplasmic reticulum membrane; endoplasmic reticulum-plasma membrane contact site; and plasma membrane. Orthologous to human GRAMD1C (GRAM domain containing 1C). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG30284 in Genome Data Viewer
    Location:
    57F6-57F6; 2-96 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (21650820..21651999, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (17538325..17539504, complement)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene antisense RNA:CR42547 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Inositol hexakisphosphate kinase Neighboring gene antisense RNA:CR43786 Neighboring gene NADH dehydrogenase (ubiquinone) B12 subunit Neighboring gene Rae1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Transcriptomic analysis of inbreeding depression in cold-sensitive Drosophila melanogaster shows upregulation of the immune response. Vermeulen CJ, et al. J Evol Biol, 2013 Sep. PMID 23944235
    2. CRISPR-based modular assembly of a UAS-cDNA/ORF plasmid library for more than 5500 Drosophila genes conserved in humans. Wei P, et al. Genome Res, 2020 Jan. PMID 31722958, Free PMC Article
    3. A global in vivo Drosophila RNAi screen identifies NOT3 as a conserved regulator of heart function. Neely GG, et al. Cell, 2010 Apr 2. PMID 20371351, Free PMC Article
    4. A genome-wide Drosophila screen for heat nociception identifies α2δ3 as an evolutionarily conserved pain gene. Neely GG, et al. Cell, 2010 Nov 12. PMID 21074052, Free PMC Article
    5. Systematic genetic analysis of muscle morphogenesis and function in Drosophila. Schnorrer F, et al. Nature, 2010 Mar 11. PMID 20220848

    See all (20) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG30284-PA
    CG30284-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      21650820..21651999 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_166468.3 → NP_726097.1  uncharacterized protein Dmel_CG30284, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_726097.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8MLV6
      Related
      FBpp0071601
      Conserved Domains (1) summary
      pfam16016
      Location:186 → 332
      DUF4782; Domain of unknown function (DUF4782)

    2. NM_166467.3 → NP_726096.1  uncharacterized protein Dmel_CG30284, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_726096.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8MKJ8
      Related
      FBpp0071602
      Conserved Domains (1) summary
      pfam16016
      Location:158 → 304
      DUF4782; Domain of unknown function (DUF4782)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8MKJ8 Q8MKJ8
    Q8MLV6 Q8MLV6

    Gene LinkOut

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