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    Alg13 Alg13 UDP-N-acetylglucosaminyltransferase subunit [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 43443, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Alg13provided by FlyBase
    Official Full Name
    Alg13 UDP-N-acetylglucosaminyltransferase subunitprovided by FlyBase
    Primary source
    FLYBASE:FBgn0039639
    Locus tag
    Dmel_CG14512
    See related
    AllianceGenome:FB:FBgn0039639
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG14512; dAlg13; Dmel\CG14512
    Summary
    Predicted to enable N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity. Predicted to be involved in dolichol-linked oligosaccharide biosynthetic process. Predicted to be part of UDP-N-acetylglucosamine transferase complex. Is expressed in adult head. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Alg13 in Genome Data Viewer
    Location:
    98F12-98F12; 3-97 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (29137970..29138573, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (24963692..24964295, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Choline transporter-like 2 Neighboring gene dim gamma-tubulin 6 Neighboring gene Vacuolar H[+] ATPase 100kD subunit 1 Neighboring gene Suppressor of ER stress-induced death Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Diversity and functions of protein glycosylation in insects. Walski T, et al. Insect Biochem Mol Biol, 2017 Apr. PMID 28232040
    2. An in vivo RNA interference screen identifies gene networks controlling Drosophila melanogaster blood cell homeostasis. Avet-Rochex A, et al. BMC Dev Biol, 2010 Jun 11. PMID 20540764, Free PMC Article
    3. Genome-Wide Mapping Targets of the Metazoan Chromatin Remodeling Factor NURF Reveals Nucleosome Remodeling at Enhancers, Core Promoters and Gene Insulators. Kwon SY, et al. PLoS Genet, 2016 Apr. PMID 27046080, Free PMC Article
    4. Investigating Developmental and Epileptic Encephalopathy Using Drosophila melanogaster. Takai A, et al. Int J Mol Sci, 2020 Sep 3. PMID 32899411, Free PMC Article
    5. Phenotype-based clustering of glycosylation-related genes by RNAi-mediated gene silencing. Yamamoto-Hino M, et al. Genes Cells, 2015 Jun. PMID 25940448, Free PMC Article

    See all (27) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables hexosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in dolichol-linked oligosaccharide biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in dolichol-linked oligosaccharide biosynthetic process ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    part_of UDP-N-acetylglucosamine transferase complex ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    Alg13 UDP-N-acetylglucosaminyltransferase subunit
    Names
    Alg13-PA
    CG14512-PA
    NP_651673.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      29137970..29138573 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_143416.1 → NP_651673.1  Alg13 UDP-N-acetylglucosaminyltransferase subunit [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_651673.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q29QL2, Q9VAP1
      Related
      FBpp0084782, FBtr0085413
      Conserved Domains (1) summary
      pfam04101
      Location:5 → 168
      Glyco_tran_28_C; Glycosyltransferase family 28 C-terminal domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VAP1 Q9VAP1

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