Scsalpha2 Succinyl-coenzyme A synthetase alpha subunit 2 [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: Scsalpha2provided by FlyBase
Official Full Name: Succinyl-coenzyme A synthetase alpha subunit 2provided by FlyBase
Primary source: FLYBASE:FBgn0038708
Locus tag: Dmel_CG6255
See related: AllianceGenome:FB:FBgn0038708
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: AAF55672; anon-WO0140519.197; CG6255; Dmel\CG6255; Scsa2
Summary: Predicted to enable succinate-CoA ligase (ADP-forming) activity and succinate-CoA ligase (GDP-forming) activity. Predicted to be involved in tricarboxylic acid cycle. Predicted to be part of succinate-CoA ligase complex (ADP-forming) and succinate-CoA ligase complex (GDP-forming). Predicted to be active in mitochondrion. Is expressed in adult head and spermatozoon. Human ortholog(s) of this gene implicated in mitochondrial DNA depletion syndrome 9. Orthologous to human SUCLG1 (succinate-CoA ligase GDP/ADP-forming subunit alpha). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
NEW: Try the new Gene table
Try the new Transcript table

Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	3R	NT_033777.3 (19461879..19463066, complement)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	3R	NT_033777.2 (15287601..15288788, complement)

Chromosome 3R - NT_033777.3 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Submit: New GeneRIF Correction

Function	Evidence Code	Pubs
enables catalytic activity	IEA Inferred from Electronic Annotation more info
enables succinate-CoA ligase (ADP-forming) activity	IBA Inferred from Biological aspect of Ancestor more info
enables succinate-CoA ligase (GDP-forming) activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in tricarboxylic acid cycle	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in mitochondrion	IBA Inferred from Biological aspect of Ancestor more info
part_of succinate-CoA ligase complex (ADP-forming)	IBA Inferred from Biological aspect of Ancestor more info
part_of succinate-CoA ligase complex (GDP-forming)	ISS Inferred from Sequence or Structural Similarity more info

NP_650809.1

NEW Try the new Transcript table

The following sections contain reference sequences that belong to a specific genome build. Explain