CG42613 uncharacterized protein [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: CG42613provided by FlyBase
Official Full Name: uncharacterized proteinprovided by FlyBase
Primary source: FLYBASE:FBgn0261262
Locus tag: Dmel_CG42613
See related: AllianceGenome:FB:FBgn0261262
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: CG14289; CG31149; CG31222; CG5449; CT17110; CT33918; dLev-10; Dmel\CG42613; tld-like
Old locus tag: Dmel_CG31149; Dmel_CG31222
Summary: Predicted to be active in plasma membrane. Is expressed in adult head. [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Genomic context

Location:: 91D5-91E1; 3-65 cM

Exon count:: 23

Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	3R	NT_033777.3 (18929196..18978088)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	3R	NT_033777.2 (14754918..14803810)

Chromosome 3R - NT_033777.3 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by FlyBase

Function	Evidence Code	Pubs
enables molecular_function	ND No biological Data available more info

Component	Evidence Code	Pubs
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: uncharacterized protein

Names: CG42613-PE; CG42613-PF; CG42613-PG; CG42613-PH; CG42613-PI

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NT_033777.3 Reference assembly

Range

18929196..18978088

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_001260256.1 → NP_001247185.1 uncharacterized protein Dmel_CG42613, isoform E [Drosophila melanogaster]

See identical proteins and their annotated locations for NP_001247185.1

Status: REVIEWED

UniProtKB/TrEMBL

A0A0B4K760

Conserved Domains (2) summary

cd00041
Location:421 → 541

CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.

cd00112
Location:987 → 1022

LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
NM_001414099.1 → NP_001401046.1 uncharacterized protein Dmel_CG42613, isoform I [Drosophila melanogaster]

Status: REVIEWED
NM_169844.4 → NP_732390.3 uncharacterized protein Dmel_CG42613, isoform H [Drosophila melanogaster]

See identical proteins and their annotated locations for NP_732390.3

Status: REVIEWED

UniProtKB/TrEMBL

Q9VE20

Conserved Domains (2) summary

cd00041
Location:388 → 508

CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.

cd00112
Location:954 → 989

LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
NM_001260258.1 → NP_001247187.1 uncharacterized protein Dmel_CG42613, isoform G [Drosophila melanogaster]

See identical proteins and their annotated locations for NP_001247187.1

Status: REVIEWED

UniProtKB/TrEMBL

A0A0B4K6C8

Conserved Domains (2) summary

cd00041
Location:388 → 508

CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.

cd00112
Location:954 → 989

LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
NM_001260257.2 → NP_001247186.1 uncharacterized protein Dmel_CG42613, isoform F [Drosophila melanogaster]

See identical proteins and their annotated locations for NP_001247186.1

Status: REVIEWED

UniProtKB/TrEMBL

A0A0B4K686, D0IQI1

Conserved Domains (3) summary

cd00041
Location:78 → 198

CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.

cd00112
Location:644 → 679

LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...

cl00049
Location:17 → 61

CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.