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    Y66D12A.8 STING ER exit protein [ Caenorhabditis elegans ]

    Gene ID: 176589, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Y66D12A.8
    Official Full Name
    STING ER exit protein
    Primary source
    WormBase:WBGene00013434
    Locus tag
    CELE_Y66D12A.8
    See related
    AllianceGenome:WB:WBGene00013434
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in endoplasmic reticulum membrane organization and endoplasmic reticulum to Golgi vesicle-mediated transport. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in non-syndromic X-linked intellectual disability 107. Orthologous to human STEEP1 (STING1 ER exit protein 1). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See Y66D12A.8 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    3
    Sequence:
    Chromosome: III; NC_003281.10 (11574221..11578719)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene MITD1 C-terminal phospholipase D-like domain-containing protein Neighboring gene Proteasome activator PA28 C-terminal domain-containing protein;Proteasome activator complex subunit 3 Neighboring gene Glutamyl-tRNA(Gln) amidotransferase subunit C, mitochondrial Neighboring gene Uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003281.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. FACT Sets a Barrier for Cell Fate Reprogramming in Caenorhabditis elegans and Human Cells. Kolundzic E, et al. Dev Cell, 2018 Sep 10. PMID 30078731, Free PMC Article
    2. SIN-3 acts in distinct complexes to regulate the germline transcriptional program in Caenorhabditis elegans. Robert VJ, et al. Development, 2023 Nov 1. PMID 37818613, Free PMC Article
    3. A modified TurboID approach identifies tissue-specific centriolar components in C. elegans. Holzer E, et al. PLoS Genet, 2022 Apr. PMID 35442950, Free PMC Article
    4. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
    5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in endoplasmic reticulum membrane organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in endoplasmic reticulum to Golgi vesicle-mediated transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    STING ER exit protein
    NP_001255130.2
    • Partially confirmed by transcript evidence
    NP_001255131.2
    • Partially confirmed by transcript evidence
    NP_001255132.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      11574221..11578719
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001268201.5 → NP_001255130.2  STING ER exit protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001255130.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q95Q06

    2. NM_001268202.5 → NP_001255131.2  STING ER exit protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001255131.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      G2HK16

    3. NM_001268203.3 → NP_001255132.1  STING ER exit protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001255132.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      G2HK17
    Nucleotide Protein
    Heading Accession and Version

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