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    T01B7.5 Sas10 C-terminal domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 174395, updated on 9-Dec-2024

    Summary

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    Official Symbol
    T01B7.5
    Official Full Name
    Sas10 C-terminal domain-containing protein
    Primary source
    WormBase:WBGene00011311
    Locus tag
    CELE_T01B7.5
    See related
    AllianceGenome:WB:WBGene00011311
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Predicted to be part of small-subunit processome. Predicted to be active in nucleolus. Orthologous to human UTP3 (UTP3 small subunit processome component). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See T01B7.5 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    9
    Sequence:
    Chromosome: II; NC_003280.10 (8716828..8721688)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Ras-related protein Rab-21 Neighboring gene Secreted protein Neighboring gene Peptidyl-prolyl cis-trans isomerase 11 Neighboring gene TRansport of membrane to Cell Surface Neighboring gene Activin_recp domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Integrating interactome, phenome, and transcriptome mapping data for the C. elegans germline. Walhout AJ, et al. Curr Biol, 2002 Nov 19. PMID 12445390
    2. Germline Maintenance Through the Multifaceted Activities of GLH/Vasa in Caenorhabditis elegans P Granules. Marnik EA, et al. Genetics, 2019 Nov. PMID 31506335, Free PMC Article
    3. Empirically controlled mapping of the Caenorhabditis elegans protein-protein interactome network. Simonis N, et al. Nat Methods, 2009 Jan. PMID 19123269, Free PMC Article
    4. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article
    5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleolus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of small-subunit processome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Sas10 C-terminal domain-containing protein
    NP_001022291.1
    • Confirmed by transcript evidence
    NP_001379438.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      8716828..8721688
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001393139.1 → NP_001379438.1  Sas10 C-terminal domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q58AA7
      Conserved Domains (1) summary
      pfam09368
      Location:113 → 187
      Sas10; Sas10 C-terminal domain

    2. NM_001027120.3 → NP_001022291.1  Sas10 C-terminal domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001022291.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q22046
      Conserved Domains (1) summary
      pfam09368
      Location:331 → 405
      Sas10; Sas10 C-terminal domain
    Nucleotide Protein
    Heading Accession and Version

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