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    phf-15 PHD-type domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 175435, updated on 9-Dec-2024

    Summary

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    Official Symbol
    phf-15
    Official Full Name
    PHD-type domain-containing protein
    Primary source
    WormBase:WBGene00021810
    Locus tag
    CELE_Y53G8AR.2
    See related
    AllianceGenome:WB:WBGene00021810
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable histone binding activity and nucleosome binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Orthologous to several human genes including JADE3 (jade family PHD finger 3). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See phf-15 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    11
    Sequence:
    Chromosome: III; NC_003281.10 (3322853..3331727)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Small monomeric GTPase Neighboring gene C3H1-type domain-containing protein Neighboring gene Secreted protein Neighboring gene tRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003281.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Diverse chromatin remodeling genes antagonize the Rb-involved SynMuv pathways in C. elegans. Cui M, et al. PLoS Genet, 2006 May. PMID 16710447, Free PMC Article
    2. A transcriptional cofactor regulatory network for the C. elegans intestine. Horowitz BB, et al. G3 (Bethesda), 2023 Jul 5. PMID 37119809, Free PMC Article
    3. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    4. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
    5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of MOZ/MORF histone acetyltransferase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    PHD-type domain-containing protein
    NP_497691.1
    • Confirmed by transcript evidence
    NP_871639.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      3322853..3331727
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_065290.5 → NP_497691.1  PHD-type domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_497691.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9N3F6
      Conserved Domains (2) summary
      cd15492
      Location:281 → 327
      PHD_BRPF_JADE_like; PHD finger found in BRPF proteins, Jade proteins, protein AF-10, AF-17, and similar proteins
      pfam13832
      Location:336 → 450
      zf-HC5HC2H_2; PHD-zinc-finger like domain

    2. NM_181910.4 → NP_871639.1  PHD-type domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_871639.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8IAA4
      Conserved Domains (2) summary
      cd15492
      Location:240 → 286
      PHD_BRPF_JADE_like; PHD finger found in BRPF proteins, Jade proteins, protein AF-10, AF-17, and similar proteins
      pfam13832
      Location:295 → 409
      zf-HC5HC2H_2; PHD-zinc-finger like domain
    Nucleotide Protein
    Heading Accession and Version

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