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    lea-1 Plant Late Embryo Abundant (LEA) related [ Caenorhabditis elegans ]

    Gene ID: 3564838, updated on 9-Dec-2024

    Summary

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    Official Symbol
    lea-1
    Official Full Name
    Plant Late Embryo Abundant (LEA) related
    Primary source
    WormBase:WBGene00002263
    Locus tag
    CELE_K08H10.1
    See related
    AllianceGenome:WB:WBGene00002263
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable lipid binding activity. Involved in hyperosmotic response; response to desiccation; and response to heat. Predicted to be located in extracellular region. Is expressed in several structures, including excretory cell; germ line; head; intestine; and tail neurons. Orthologous to human PLIN4 (perilipin 4). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See lea-1 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    12
    Sequence:
    Chromosome: V; NC_003283.11 (10011923..10028168)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Nucleoside-diphosphatase uda-1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene 1-acylglycerol-3-phosphate O-acyltransferase;Putative 1-acyl-sn-glycerol-3-phosphate acyltransferase acl-2 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. LEA motifs promote desiccation tolerance in vivo.
      Title: LEA motifs promote desiccation tolerance in vivo.
    2. Accumulation of Glycogen and Upregulation of LEA-1 in C. elegans daf-2(e1370) Support Stress Resistance, Not Longevity.
      Title: Accumulation of Glycogen and Upregulation of LEA-1 in C. elegans daf-2(e1370) Support Stress Resistance, Not Longevity.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables lipid binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in hyperosmotic response IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in lipid transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in lipoprotein metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in response to desiccation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in response to desiccation ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    involved_in response to heat IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Plant Late Embryo Abundant (LEA) related
    NP_001256160.1
    • Confirmed by transcript evidence
    NP_001256161.1
    • Confirmed by transcript evidence
    NP_001256162.1
    • Confirmed by transcript evidence
    NP_001256163.1
    • Confirmed by transcript evidence
    NP_001256164.1
    • Confirmed by transcript evidence
    NP_001256165.1
    • Confirmed by transcript evidence
    NP_001256169.1
    • Confirmed by transcript evidence
    NP_001256170.1
    • Confirmed by transcript evidence
    NP_001256171.1
    • Confirmed by transcript evidence
    NP_001256173.1
    • Confirmed by transcript evidence
    NP_001256174.1
    • Confirmed by transcript evidence
    NP_001360513.1
    • Confirmed by transcript evidence
    NP_001360514.1
    • Confirmed by transcript evidence
    NP_001360515.1
    • Confirmed by transcript evidence
    NP_001360516.1
    • Confirmed by transcript evidence
    NP_001360517.1
    • Confirmed by transcript evidence
    NP_001360518.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      10011923..10028168
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001373086.2 → NP_001360514.1  Plant Late Embryo Abundant (LEA) related [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A486WVD1
      Conserved Domains (2) summary
      PTZ00121
      Location:760 → 1269
      PTZ00121; MAEBL; Provisional
      pfam01442
      Location:275 → 458
      Apolipoprotein; Apolipoprotein A1/A4/E domain

    2. NM_001373085.2 → NP_001360513.1  Plant Late Embryo Abundant (LEA) related [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A486WUR9
      Conserved Domains (2) summary
      PTZ00121
      Location:452 → 1141
      PTZ00121; MAEBL; Provisional
      PRK05035
      Location:1060 → 1294
      PRK05035; electron transport complex protein RnfC; Provisional

    3. NM_001269232.3 → NP_001256161.1  Plant Late Embryo Abundant (LEA) related [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001256161.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      H2FLK7
      Conserved Domains (2) summary
      pfam01442
      Location:821 → 989
      Apolipoprotein; Apolipoprotein A1/A4/E domain
      cl01888
      Location:761 → 830
      DUF883; Bacterial protein of unknown function (DUF883)

    4. NM_001269231.3 → NP_001256160.1  Plant Late Embryo Abundant (LEA) related [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001256160.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      H2FLL1
      Conserved Domains (2) summary
      pfam01442
      Location:945 → 1113
      Apolipoprotein; Apolipoprotein A1/A4/E domain
      cl01888
      Location:885 → 954
      DUF883; Bacterial protein of unknown function (DUF883)

    5. NM_001269233.4 → NP_001256162.1  Plant Late Embryo Abundant (LEA) related [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001256162.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      H2FLK5
      Conserved Domains (1) summary
      pfam01442
      Location:214 → 371
      Apolipoprotein; Apolipoprotein A1/A4/E domain

    6. NM_001269234.3 → NP_001256163.1  Plant Late Embryo Abundant (LEA) related [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001256163.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      H2FLK8
      Conserved Domains (2) summary
      pfam01442
      Location:929 → 1097
      Apolipoprotein; Apolipoprotein A1/A4/E domain
      cl01888
      Location:869 → 938
      DUF883; Bacterial protein of unknown function (DUF883)

    7. NM_001373087.2 → NP_001360515.1  Plant Late Embryo Abundant (LEA) related [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A486WVH0
      Conserved Domains (2) summary
      PTZ00121
      Location:436 → 1125
      PTZ00121; MAEBL; Provisional
      PRK05035
      Location:1044 → 1278
      PRK05035; electron transport complex protein RnfC; Provisional

    8. NM_001373088.2 → NP_001360516.1  Plant Late Embryo Abundant (LEA) related [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A486WWP8
      Conserved Domains (2) summary
      PTZ00121
      Location:744 → 1253
      PTZ00121; MAEBL; Provisional
      pfam01442
      Location:259 → 442
      Apolipoprotein; Apolipoprotein A1/A4/E domain

    9. NM_001269235.3 → NP_001256164.1  Plant Late Embryo Abundant (LEA) related [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001256164.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      H2FLK9
      Conserved Domains (2) summary
      pfam01442
      Location:805 → 973
      Apolipoprotein; Apolipoprotein A1/A4/E domain
      cl01888
      Location:745 → 814
      DUF883; Bacterial protein of unknown function (DUF883)

    10. NM_001269236.3 → NP_001256165.1  Plant Late Embryo Abundant (LEA) related [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001256165.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      H2FLK3
      Conserved Domains (1) summary
      pfam01442
      Location:198 → 355
      Apolipoprotein; Apolipoprotein A1/A4/E domain

    11. NM_001269242.2 → NP_001256171.1  Plant Late Embryo Abundant (LEA) related [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001256171.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      G5EFU3
      Conserved Domains (1) summary
      pfam01442
      Location:126 → 283
      Apolipoprotein; Apolipoprotein A1/A4/E domain

    12. NM_001269241.4 → NP_001256170.1  Plant Late Embryo Abundant (LEA) related [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001256170.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      G5EDH9
      Conserved Domains (2) summary
      pfam01442
      Location:733 → 901
      Apolipoprotein; Apolipoprotein A1/A4/E domain
      cl01888
      Location:673 → 742
      DUF883; Bacterial protein of unknown function (DUF883)

    13. NM_001269240.3 → NP_001256169.1  Plant Late Embryo Abundant (LEA) related [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001256169.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      G5EEF0
      Conserved Domains (2) summary
      pfam01442
      Location:857 → 1025
      Apolipoprotein; Apolipoprotein A1/A4/E domain
      cl01888
      Location:797 → 866
      DUF883; Bacterial protein of unknown function (DUF883)

    14. NM_001373089.2 → NP_001360517.1  Plant Late Embryo Abundant (LEA) related [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A486WXP6
      Conserved Domains (2) summary
      PTZ00121
      Location:364 → 1053
      PTZ00121; MAEBL; Provisional
      PRK05035
      Location:972 → 1206
      PRK05035; electron transport complex protein RnfC; Provisional

    15. NM_001373090.2 → NP_001360518.1  Plant Late Embryo Abundant (LEA) related [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A486WTP6
      Conserved Domains (1) summary
      PTZ00121
      Location:672 → 1181
      PTZ00121; MAEBL; Provisional

    16. NM_001269244.3 → NP_001256173.1  Plant Late Embryo Abundant (LEA) related [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001256173.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      G5EBW6
      Conserved Domains (2) summary
      pfam01442
      Location:104 → 272
      Apolipoprotein; Apolipoprotein A1/A4/E domain
      cl01888
      Location:44 → 113
      DUF883; Bacterial protein of unknown function (DUF883)

    17. NM_001269245.3 → NP_001256174.1  Plant Late Embryo Abundant (LEA) related [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001256174.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      G5EGB8
      Conserved Domains (2) summary
      pfam01442
      Location:104 → 272
      Apolipoprotein; Apolipoprotein A1/A4/E domain
      cl01888
      Location:44 → 113
      DUF883; Bacterial protein of unknown function (DUF883)
    Nucleotide Protein
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