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    akap-1 KH domain-containing protein akap-1;Tudor domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 175898, updated on 9-Dec-2024

    Summary

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    Official Symbol
    akap-1
    Official Full Name
    KH domain-containing protein akap-1;Tudor domain-containing protein
    Primary source
    WormBase:WBGene00016977
    Locus tag
    CELE_C56G2.1
    See related
    AllianceGenome:WB:WBGene00016977
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable RNA binding activity. Predicted to be located in membrane and mitochondrion. Is expressed in several structures, including gonad. Orthologous to human AKAP1 (A-kinase anchoring protein 1). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See akap-1 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    16
    Sequence:
    Chromosome: III; NC_003281.10 (6353384..6366661)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene tRNA MethylTransferase Neighboring gene Uncharacterized protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene N-acetyltransferase domain-containing protein Neighboring gene THO complex subunit 2 Neighboring gene ncRNA Neighboring gene Small ribosomal subunit protein uS15

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003281.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Misexpression of the Caenorhabditis elegans miRNA let-7 is sufficient to drive developmental programs. Hayes GD, et al. Cold Spring Harb Symp Quant Biol, 2006. PMID 17381276
    2. Conserved RNA-binding proteins required for dendrite morphogenesis in Caenorhabditis elegans sensory neurons. Antonacci S, et al. G3 (Bethesda), 2015 Feb 10. PMID 25673135, Free PMC Article
    3. Lifespan regulation by evolutionarily conserved genes essential for viability. Curran SP, et al. PLoS Genet, 2007 Apr 6. PMID 17411345, Free PMC Article
    4. A transcriptional cofactor regulatory network for the C. elegans intestine. Horowitz BB, et al. G3 (Bethesda), 2023 Jul 5. PMID 37119809, Free PMC Article
    5. The RNA-binding protein repertoire of Arabidopsis thaliana. Marondedze C, et al. Sci Rep, 2016 Jul 11. PMID 27405932, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    KH domain-containing protein akap-1;Tudor domain-containing protein
    NP_001348742.1
    • Confirmed by transcript evidence
    NP_001348743.1
    • Confirmed by transcript evidence
    NP_001348744.1
    • Confirmed by transcript evidence
    NP_001370528.1
    • Confirmed by transcript evidence
    NP_741191.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      6353384..6366661
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001382893.2 → NP_001370528.1  KH domain-containing protein akap-1 [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q09285, Q09286
      Conserved Domains (4) summary
      PTZ00121
      Location:183 → 477
      PTZ00121; MAEBL; Provisional
      cd20407
      Location:686 → 761
      Tudor_AKAP1; Tudor domain found in mitochondrial A-kinase anchor protein 1 (AKAP1) and similar proteins
      NF033930
      Location:181 → 328
      pneumo_PspA; pneumococcal surface protein A
      cd22395
      Location:530 → 600
      KH-I_AKAP1; type I K homology (KH) RNA-binding domain found in mitochondrial A-kinase anchor protein 1 (AKAP1) and similar proteins

    2. NM_001361723.3 → NP_001348743.1  Tudor domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A2K5ATV3
      Conserved Domains (3) summary
      pfam00013
      Location:525 → 590
      KH_1; KH domain
      pfam00567
      Location:635 → 751
      TUDOR; Tudor domain
      pfam16001
      Location:193 → 350
      DUF4775; Domain of unknown function (DUF4775)

    3. NM_001361724.3 → NP_001348742.1  Tudor domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A2K5ATU1
      Conserved Domains (3) summary
      pfam00013
      Location:511 → 576
      KH_1; KH domain
      pfam00567
      Location:621 → 737
      TUDOR; Tudor domain
      pfam16001
      Location:193 → 350
      DUF4775; Domain of unknown function (DUF4775)

    4. NM_001361725.3 → NP_001348744.1  Tudor domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A2K5ATU5
      Conserved Domains (3) summary
      pfam00013
      Location:431 → 496
      KH_1; KH domain
      pfam00567
      Location:541 → 657
      TUDOR; Tudor domain
      pfam16001
      Location:93 → 256
      DUF4775; Domain of unknown function (DUF4775)

    5. NM_171164.7 → NP_741191.1  KH domain-containing protein akap-1 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_741191.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q09285
      Conserved Domains (3) summary
      smart00333
      Location:235 → 286
      TUDOR; Tudor domain
      pfam00013
      Location:73 → 137
      KH_1; KH domain
      pfam00567
      Location:176 → 300
      TUDOR; Tudor domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q09285.2

    Gene LinkOut

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