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    phf-10 PHD finger protein 10;PHD-type domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 3565141, updated on 9-Dec-2024

    Summary

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    Official Symbol
    phf-10
    Official Full Name
    PHD finger protein 10;PHD-type domain-containing protein
    Primary source
    WormBase:WBGene00018013
    Locus tag
    CELE_F33E11.6
    See related
    AllianceGenome:WB:WBGene00018013
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable metal ion binding activity. Predicted to be involved in nervous system development. Predicted to be located in nucleus. Used to study alcohol use disorder. Orthologous to human PHF10 (PHD finger protein 10). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See phf-10 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    7
    Sequence:
    Chromosome: V; NC_003283.11 (304810..311565, complement)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene 'chromo' domain containing protein;Mediator complex subunit 6 Neighboring gene Protein phosphatase 1 regulatory subunit 21 N-terminal domain-containing protein Neighboring gene Nuclear Hormone Receptor family Neighboring gene ncRNA Neighboring gene ABC transporter domain-containing protein Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. New alleles of the SWI/SNF chromatin remodeling complex gene phf-10. Mathies LD, et al. MicroPubl Biol, 2022. PMID 35622521, Free PMC Article
    2. SWI/SNF chromatin remodeling regulates alcohol response behaviors in Caenorhabditis elegans and is associated with alcohol dependence in humans. Mathies LD, et al. Proc Natl Acad Sci U S A, 2015 Mar 10. PMID 25713357, Free PMC Article
    3. DEPS-1 is required for piRNA-dependent silencing and PIWI condensate organisation in Caenorhabditis elegans. Suen KM, et al. Nat Commun, 2020 Aug 25. PMID 32843637, Free PMC Article
    4. A transcriptional cofactor regulatory network for the C. elegans intestine. Horowitz BB, et al. G3 (Bethesda), 2023 Jul 5. PMID 37119809, Free PMC Article
    5. RNA targets and specificity of Staufen, a double-stranded RNA-binding protein in Caenorhabditis elegans. LeGendre JB, et al. J Biol Chem, 2013 Jan 25. PMID 23195953, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in nervous system development IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    PHD finger protein 10;PHD-type domain-containing protein
    NP_001041112.1
    • Partially confirmed by transcript evidence
    NP_001041113.1
    • Confirmed by transcript evidence
    NP_001300097.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      304810..311565 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001047648.4 → NP_001041113.1  PHD finger protein 10 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001041113.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q2A950
      Conserved Domains (2) summary
      cd15528
      Location:334 → 380
      PHD1_PHF10; PHD finger 1 found in PHD finger protein 10 (PHF10) and similar proteins
      cd15529
      Location:382 → 424
      PHD2_PHF10; PHD finger 2 found in PHD finger protein 10 (PHF10) and similar proteins

    2. NM_001313168.3 → NP_001300097.1  PHD-type domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0K3AS00
      Conserved Domains (1) summary
      cl22851
      Location:38 → 80
      PHD_SF; PHD finger superfamily

    3. NM_001047647.6 → NP_001041112.1  PHD finger protein 10 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001041112.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q2A949
    Nucleotide Protein
    Heading Accession and Version

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