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    pcp-1 Putative serine protease pcp-1 [ Caenorhabditis elegans ]

    Gene ID: 176086, updated on 9-Dec-2024

    Summary

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    Official Symbol
    pcp-1
    Official Full Name
    Putative serine protease pcp-1
    Primary source
    WormBase:WBGene00003956
    Locus tag
    CELE_ZK112.1
    See related
    AllianceGenome:WB:WBGene00003956
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable dipeptidyl-peptidase activity. Predicted to be involved in proteolysis. Is expressed in intestine. Orthologous to human PRCP (prolylcarboxypeptidase). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See pcp-1 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    7
    Sequence:
    Chromosome: III; NC_003281.10 (7758903..7761262)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene B box-type domain-containing protein;B-box type zinc finger protein ncl-1;RING-type E3 ubiquitin transferase Neighboring gene AMP-binding domain-containing protein Neighboring gene Cadherin-3 Neighboring gene ncRNA Neighboring gene Metaxin-2 homolog Neighboring gene Putative ATP-dependent RNA helicase ZK686.2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003281.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Improved Biocompatibility of Amino-Functionalized Graphene Oxide in Caenorhabditis elegans. Rive C, et al. Small, 2019 Nov. PMID 31576668
    2. SGPL1 stimulates VPS39 recruitment to the mitochondria in MICU1 deficient cells. Jackson J, et al. Mol Metab, 2022 Jul. PMID 35452878, Free PMC Article
    3. Antagonistic fungal enterotoxins intersect at multiple levels with host innate immune defences. Zhang X, et al. PLoS Genet, 2021 Jun. PMID 34166401, Free PMC Article
    4. Germline Maintenance Through the Multifaceted Activities of GLH/Vasa in Caenorhabditis elegans P Granules. Marnik EA, et al. Genetics, 2019 Nov. PMID 31506335, Free PMC Article
    5. Screening for cold tolerance genes in C. elegans, whose expressions are affected by anticancer drugs camptothecin and leptomycin B. Okahata M, et al. Sci Rep, 2024 Mar 5. PMID 38443452, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables dipeptidyl-peptidase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables serine-type exopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables serine-type peptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Putative serine protease pcp-1
    NP_498688.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      7758903..7761262
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_066287.7 → NP_498688.1  Putative serine protease pcp-1 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_498688.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P34610
      Conserved Domains (1) summary
      cl21494
      Location:50 → 498
      Abhydrolase; alpha/beta hydrolases
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P34610.2

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