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    Y71G12B.31 Protein-tyrosine phosphatase;Tyrosine-protein phosphatase [ Caenorhabditis elegans ]

    Gene ID: 3565511, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Y71G12B.31
    Official Full Name
    Protein-tyrosine phosphatase;Tyrosine-protein phosphatase
    Primary source
    WormBase:WBGene00044348
    Locus tag
    CELE_Y71G12B.31
    See related
    AllianceGenome:WB:WBGene00044348
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable protein tyrosine phosphatase activity. Predicted to be involved in signal transduction. Predicted to be located in membrane. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See Y71G12B.31 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    10
    Sequence:
    Chromosome: I; NC_003279.8 (1686216..1693457, complement)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene DUF4476 domain-containing protein Neighboring gene Repulsive guidance molecule B homolog drag-1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene UBC core domain-containing protein;UBIQUITIN_CONJUGAT_2 domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables protein tyrosine phosphatase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables protein tyrosine phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in motor neuron axon guidance IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in protein dephosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Protein-tyrosine phosphatase;Tyrosine-protein phosphatase
    NP_001293450.1
    • Partially confirmed by transcript evidence
    NP_001293451.1
    • Partially confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      1686216..1693457 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001306521.1 → NP_001293450.1  Tyrosine-protein phosphatase [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001293450.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      W6RR46
      Conserved Domains (2) summary
      cd00047
      Location:170 → 414
      PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
      pfam00102
      Location:170 → 412
      Y_phosphatase; Protein-tyrosine phosphatase

    2. NM_001306522.1 → NP_001293451.1  Protein-tyrosine phosphatase [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001293451.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      W6RYA7
      Conserved Domains (1) summary
      cl21483
      Location:2 → 155
      PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
    Nucleotide Protein
    Heading Accession and Version

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