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    M04C9.1 Pyroglutamyl-peptidase 1 [ Caenorhabditis elegans ]

    Gene ID: 187438, updated on 9-Dec-2024

    Summary

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    Official Symbol
    M04C9.1
    Official Full Name
    Pyroglutamyl-peptidase 1
    Primary source
    WormBase:WBGene00010856
    Locus tag
    CELE_M04C9.1
    See related
    AllianceGenome:WB:WBGene00010856
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable cysteine-type peptidase activity. Predicted to be involved in proteolysis. Orthologous to human PGPEP1L (pyroglutamyl-peptidase I like). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See M04C9.1 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    7
    Sequence:
    Chromosome: I; NC_003279.8 (9350269..9352700, complement)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Protein lin-41 Neighboring gene Aspartoacylase Neighboring gene Pyroglutamyl-peptidase 1 Neighboring gene Wsv419

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables cysteine-type peptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Pyroglutamyl-peptidase 1
    NP_001122498.1
    • Confirmed by transcript evidence
    NP_001122499.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      9350269..9352700 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001129026.3 → NP_001122498.1  Pyroglutamyl-peptidase 1 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001122498.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A5JYY7
      Conserved Domains (1) summary
      pfam06162
      Location:13 → 173
      PgaPase_1; Putative pyroglutamyl peptidase PgaPase_1

    2. NM_001129027.4 → NP_001122499.1  Pyroglutamyl-peptidase 1 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001122499.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A5JYY8
      Conserved Domains (1) summary
      cl00237
      Location:1 → 158
      Peptidase_C15; Pyroglutamyl peptidase (PGP) type I, also known as pyrrolidone carboxyl peptidase (pcp) type I: Enzymes responsible for cleaving pyroglutamate (pGlu) from the N-terminal end of specialized proteins. The N-terminal pGlu protects these proteins from ...
    Nucleotide Protein
    Heading Accession and Version

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