acl-9 Phospholipid/glycerol acyltransferase domain-containing protein [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: acl-9
Official Full Name: Phospholipid/glycerol acyltransferase domain-containing protein
Primary source: WormBase:WBGene00022646
Locus tag: CELE_ZK40.1
See related: AllianceGenome:WB:WBGene00022646
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable acyltransferase activity. Predicted to be involved in phosphatidylinositol acyl-chain remodeling. Predicted to be located in membrane. Predicted to be active in endoplasmic reticulum. Orthologous to human LCLAT1 (lysocardiolipin acyltransferase 1). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See acl-9 in Genome Data Viewer

Location:: chromosome: V

Exon count:: 5

Sequence:: Chromosome: V; NC_003283.11 (6453226..6454965)

Chromosome V - NC_003283.11 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Study identified acl-8, -9, and -10, which are closely related to each other, and ipla-1 as strong candidates for genes involved in fatty acid remodeling at the sn-1 position of phosphatidylinositol.
Title: Intracellular phospholipase A1 and acyltransferase, which are involved in Caenorhabditis elegans stem cell divisions, determine the sn-1 fatty acyl chain of phosphatidylinositol.

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

ZK40.1 (e-PCR)
- UniSTS:310483

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables acyltransferase activity	IBA Inferred from Biological aspect of Ancestor more info
enables acyltransferase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in phosphatidylinositol acyl-chain remodeling	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in endomembrane system	IBA Inferred from Biological aspect of Ancestor more info
is_active_in endoplasmic reticulum	IBA Inferred from Biological aspect of Ancestor more info
located_in membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: Phospholipid/glycerol acyltransferase domain-containing protein

NP_504644.1

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003283.11 Reference assembly

Range

6453226..6454965

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_072243.10 → NP_504644.1 Phospholipid/glycerol acyltransferase domain-containing protein [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_504644.1

Status: REVIEWED

UniProtKB/TrEMBL

Q23087

Conserved Domains (2) summary

cd07990
Location:72 → 264

LPLAT_LCLAT1-like; Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LCLAT1-like

pfam16076
Location:258 → 301

Acyltransf_C; Acyltransferase C-terminus