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    tgn-38 Trans-Golgi network integral membrane protein 2 [ Caenorhabditis elegans ]

    Gene ID: 178137, updated on 9-Dec-2024

    Summary

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    Official Symbol
    tgn-38
    Official Full Name
    Trans-Golgi network integral membrane protein 2
    Primary source
    WormBase:WBGene00011742
    Locus tag
    CELE_T12G3.7
    See related
    AllianceGenome:WB:WBGene00011742
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be located in membrane. Orthologous to human C5orf15 (chromosome 5 open reading frame 15) and TGOLN2 (trans-golgi network protein 2). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See tgn-38 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    4
    Sequence:
    Chromosome: IV; NC_003282.8 (12026882..12029174, complement)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene Spermatogenesis-defective protein spe-17 Neighboring gene LIPaSe related Neighboring gene Uncharacterized protein Neighboring gene RWD domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003282.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Triggered Golgi membrane enrichment promotes PtdIns(4,5)P2 generation for plasma membrane repair. Meng X, et al. J Cell Biol, 2023 Aug 7. PMID 37158801, Free PMC Article
    2. Conserved NIMA kinases regulate multiple steps of endocytic trafficking. Joseph BB, et al. PLoS Genet, 2023 Apr. PMID 37099601, Free PMC Article
    3. A TOCA/CDC-42/PAR/WAVE functional module required for retrograde endocytic recycling. Bai Z, et al. Proc Natl Acad Sci U S A, 2015 Mar 24. PMID 25775511, Free PMC Article
    4. Presynaptic autophagy is coupled to the synaptic vesicle cycle via ATG-9. Yang S, et al. Neuron, 2022 Mar 2. PMID 35065714, Free PMC Article
    5. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Trans-Golgi network integral membrane protein 2
    NP_001255605.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      12026882..12029174 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001268676.2 → NP_001255605.1  Trans-Golgi network integral membrane protein 2 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001255605.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      G5EFW0
      Conserved Domains (1) summary
      COG5271
      Location:24 → 263
      MDN1; Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis]
    Nucleotide Protein
    Heading Accession and Version

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