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    fut-2 Galactoside 2-alpha-L-fucosyltransferase [ Caenorhabditis elegans ]

    Gene ID: 184050, updated on 9-Dec-2024

    Summary

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    Official Symbol
    fut-2
    Official Full Name
    Galactoside 2-alpha-L-fucosyltransferase
    Primary source
    WormBase:WBGene00001506
    Locus tag
    CELE_EGAP9.2
    See related
    AllianceGenome:WB:WBGene00001506
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Enables galactoside 2-alpha-L-fucosyltransferase activity. Involved in macromolecule glycosylation. Predicted to be located in Golgi cisterna membrane. Is expressed in intestinal cell. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See fut-2 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    10
    Sequence:
    Chromosome: V; NC_003283.11 (6573939..6575890, complement)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Methyltransf_11 domain-containing protein Neighboring gene pseudo Neighboring gene C2H2-type domain-containing protein Neighboring gene L-Fucosyltransferase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Molecular cloning and characterization of a novel alpha 1,2-fucosyltransferase (CE2FT-1) from Caenorhabditis elegans. Zheng Q, et al. J Biol Chem, 2002 Oct 18. PMID 12163507
    2. A novel alpha1,2-fucosyltransferase (CE2FT-2) in Caenorhabditis elegans generates H-type 3 glycan structures. Zheng Q, et al. Glycobiology, 2008 Apr. PMID 18252778
    3. Carbohydrates and glycosylation. Berninsone PM. WormBook, 2006 Dec 18. PMID 18050430, Free PMC Article
    4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables galactoside 2-alpha-L-fucosyltransferase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables galactoside 2-alpha-L-fucosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables glycosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in carbohydrate metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in macromolecule glycosylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in macromolecule glycosylation IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in protein glycosylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in Golgi apparatus IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in Golgi cisterna membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Galactoside 2-alpha-L-fucosyltransferase
    NP_504671.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      6573939..6575890 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_072270.2 → NP_504671.1  Galactoside 2-alpha-L-fucosyltransferase [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_504671.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P91200
      Conserved Domains (1) summary
      cd11301
      Location:65 → 335
      Fut1_Fut2_like; Alpha-1,2-fucosyltransferase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P91200.1

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