U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    bre-2 Beta-1,3-galactosyltransferase bre-2;Hexosyltransferase [ Caenorhabditis elegans ]

    Gene ID: 189753, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    bre-2
    Official Full Name
    Beta-1,3-galactosyltransferase bre-2;Hexosyltransferase
    Primary source
    WormBase:WBGene00000267
    Locus tag
    CELE_Y39E4B.9
    See related
    AllianceGenome:WB:WBGene00000267
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable acetylglucosaminyltransferase activity. Involved in response to toxic substance. Predicted to be located in Golgi apparatus and membrane. Predicted to be active in Golgi membrane. [provided by Alliance of Genome Resources, Dec 2024]
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See bre-2 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    9
    Sequence:
    Chromosome: III; NC_003281.10 (13133906..13139626, complement)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Palmitoyltransferase Neighboring gene ncRNA Neighboring gene Zwei Ig domain protein zig-8 Neighboring gene NR LBD domain-containing protein Neighboring gene ABC transporter, class E

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003281.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Nematotoxicity of Marasmius oreades agglutinin (MOA) depends on glycolipid binding and cysteine protease activity. Wohlschlager T, et al. J Biol Chem, 2011 Sep 2. PMID 21757752, Free PMC Article
    2. Resistance to Bacillus thuringiensis toxin in Caenorhabditis elegans from loss of fucose. Barrows BD, et al. J Biol Chem, 2007 Feb 2. PMID 17135259
    3. Bacillus thuringiensis (Bt) toxin susceptibility and isolation of resistance mutants in the nematode Caenorhabditis elegans. Marroquin LD, et al. Genetics, 2000 Aug. PMID 10924467, Free PMC Article
    4. Resistance to a bacterial toxin is mediated by removal of a conserved glycosylation pathway required for toxin-host interactions. Griffitts JS, et al. J Biol Chem, 2003 Nov 14. PMID 12944392
    5. Use of RNAi as a preliminary tool for screening putative receptors of nematicidal toxins from Bacillus thuringiensis. García-Montelongo M, et al. Arch Microbiol, 2021 May. PMID 33432376

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

    Go to the top of the page

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables acetylglucosaminyltransferase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables glycosyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables glycosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables hexosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in protein O-linked glycosylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in protein glycosylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in response to toxic substance IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in Golgi apparatus IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in Golgi membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in Golgi membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    Beta-1,3-galactosyltransferase bre-2;Hexosyltransferase
    NP_001255188.1
    • Confirmed by transcript evidence
    NP_001255189.1
    • Confirmed by transcript evidence
    NP_001367175.1
    • Confirmed by transcript evidence
    NP_499715.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      13133906..13139626 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_067314.4 → NP_499715.2  Beta-1,3-galactosyltransferase bre-2 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_499715.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q6QMT2
      Conserved Domains (1) summary
      cl21608
      Location:100 → 279
      Galactosyl_T; Galactosyltransferase

    2. NM_001268259.3 → NP_001255188.1  Hexosyltransferase [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001255188.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      D0Z5N7
      Conserved Domains (1) summary
      pfam01762
      Location:141 → 340
      Galactosyl_T; Galactosyltransferase

    3. NM_001268260.1 → NP_001255189.1  Hexosyltransferase [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001255189.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      C3JXF0
      Conserved Domains (1) summary
      pfam01762
      Location:141 → 342
      Galactosyl_T; Galactosyltransferase

    4. NM_001379974.3 → NP_001367175.1  Beta-1,3-galactosyltransferase bre-2 [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q6QMT2, Q9U2K3
      Conserved Domains (1) summary
      pfam01762
      Location:100 → 301
      Galactosyl_T; Galactosyltransferase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q6QMT2.1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools