ztf-6 Zinc finger protein ztf-6 [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: ztf-6
Official Full Name: Zinc finger protein ztf-6
Primary source: WormBase:WBGene00012317
Locus tag: CELE_W06H12.1
See related: AllianceGenome:WB:WBGene00012317
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable chromatin insulator sequence binding activity. Involved in asymmetric stem cell division; cell fate specification; and positive regulation of gene expression. Predicted to be active in chromosome. Is expressed in several structures, including V cell; head muscle; hypodermis; neurons; and postdeirid sensillum. [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See ztf-6 in Genome Data Viewer

Location:: chromosome: I

Exon count:: 6

Sequence:: Chromosome: I; NC_003279.8 (11206922..11211905)

Chromosome I - NC_003279.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003279.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

Y53H1A.a (e-PCR)
- UniSTS:323967

W06H12.1 (e-PCR)
- UniSTS:318610

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables chromatin insulator sequence binding	IBA Inferred from Biological aspect of Ancestor more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in asymmetric stem cell division	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in epidermal cell fate specification	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in neuron fate specification	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in positive regulation of gene expression	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in regulation of transcription by RNA polymerase II	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in chromosome	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: Zinc finger protein ztf-6

NP_492877.1

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

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Reference assembly

Genomic

NC_003279.8 Reference assembly

Range

11206922..11211905

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_060476.7 → NP_492877.1 Zinc finger protein ztf-6 [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_492877.1

Status: REVIEWED

UniProtKB/Swiss-Prot

G5EC77

Conserved Domains (2) summary

COG5189
Location:346 → 435

SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]

sd00017
Location:361 → 383

ZF_C2H2; C2H2 Zn finger [structural motif]