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    pigt-1 Phosphatidylinositol glycan, class T [ Caenorhabditis elegans ]

    Gene ID: 179519, updated on 9-Dec-2024

    Summary

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    Official Symbol
    pigt-1
    Official Full Name
    Phosphatidylinositol glycan, class T
    Primary source
    WormBase:WBGene00008918
    Locus tag
    CELE_F17C11.7
    See related
    AllianceGenome:WB:WBGene00008918
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in attachment of GPI anchor to protein. Predicted to be located in membrane. Predicted to be part of GPI-anchor transamidase complex. Human ortholog(s) of this gene implicated in multiple congenital anomalies-hypotonia-seizures syndrome 3 and paroxysmal nocturnal hemoglobinuria. Orthologous to human PIGT (phosphatidylinositol glycan anchor biosynthesis class T). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See pigt-1 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    5
    Sequence:
    Chromosome: V; NC_003283.11 (10956999..10958821, complement)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene OB domain-containing protein Neighboring gene C-type lectin domain-containing protein Neighboring gene Polysacc_synt_C domain-containing protein Neighboring gene PGG domain-containing protein Neighboring gene Vacuolar protein-sorting-associated protein 36 Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    2. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
    3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in attachment of GPI anchor to protein IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in attachment of GPI anchor to protein IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of GPI-anchor transamidase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of GPI-anchor transamidase complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Phosphatidylinositol glycan, class T
    NP_001023812.1
    • Confirmed by transcript evidence
    NP_001023813.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      10956999..10958821 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001028642.4 → NP_001023813.1  Phosphatidylinositol glycan, class T [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001023813.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q5WRN6
      Conserved Domains (1) summary
      pfam04113
      Location:18 → 452
      Gpi16; Gpi16 subunit, GPI transamidase component

    2. NM_001028641.6 → NP_001023812.1  Phosphatidylinositol glycan, class T [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001023812.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q19518
      Conserved Domains (1) summary
      pfam04113
      Location:18 → 468
      Gpi16; Gpi16 subunit, GPI transamidase component
    Nucleotide Protein
    Heading Accession and Version

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