U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    taf-12 Transcription initiation factor TFIID subunit 12 [ Caenorhabditis elegans ]

    Gene ID: 176617, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    taf-12
    Official Full Name
    Transcription initiation factor TFIID subunit 12
    Primary source
    WormBase:WBGene00006396
    Locus tag
    CELE_Y56A3A.4
    See related
    AllianceGenome:WB:WBGene00006396
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable DNA binding activity and TBP-class protein binding activity. Predicted to be involved in RNA polymerase II preinitiation complex assembly. Located in nucleus. Orthologous to human TAF12 (TATA-box binding protein associated factor 12). [provided by Alliance of Genome Resources, Dec 2024]
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See taf-12 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    7
    Sequence:
    Chromosome: III; NC_003281.10 (11862385..11869281, complement)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Membrane-bound transcription factor site-2 protease Neighboring gene L-dopachrome isomerase Neighboring gene WH2 domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003281.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Global transcriptional repression in C. elegans germline precursors by regulated sequestration of TAF-4. Guven-Ozkan T, et al. Cell, 2008 Oct 3. PMID 18854162, Free PMC Article
    2. Distinct requirements for C.elegans TAF(II)s in early embryonic transcription. Walker AK, et al. EMBO J, 2001 Sep 17. PMID 11566890, Free PMC Article
    3. Transcription mechanisms. Blackwell TK, et al. WormBook, 2006 Sep 5. PMID 18050436, Free PMC Article
    4. The Regulatory Landscape of Lineage Differentiation in a Metazoan Embryo. Du Z, et al. Dev Cell, 2015 Sep 14. PMID 26321128, Free PMC Article
    5. A transcriptional cofactor regulatory network for the C. elegans intestine. Horowitz BB, et al. G3 (Bethesda), 2023 Jul 5. PMID 37119809, Free PMC Article

    See all (15) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables TBP-class protein binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables protein heterodimerization activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in DNA-templated transcription initiation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in RNA polymerase II preinitiation complex assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of transcription factor TFIID complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of transcription factor TFIID complex IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    Transcription initiation factor TFIID subunit 12
    NP_001255144.1
    • Confirmed by transcript evidence
    NP_001255145.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      11862385..11869281 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001268216.3 → NP_001255145.1  Transcription initiation factor TFIID subunit 12 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001255145.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      C0Z3M2
      Conserved Domains (1) summary
      pfam03847
      Location:198 → 264
      TFIID_20kDa; Transcription initiation factor TFIID subunit A

    2. NM_001268215.4 → NP_001255144.1  Transcription initiation factor TFIID subunit 12 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001255144.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      C0Z3M2, Q9U226
      Conserved Domains (1) summary
      pfam03847
      Location:231 → 297
      TFIID_20kDa; Transcription initiation factor TFIID subunit A
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9U226.2

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools
    Miscellaneous