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    emc-3 ER membrane protein complex subunit 3 [ Caenorhabditis elegans ]

    Gene ID: 178300, updated on 9-Dec-2024

    Summary

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    Official Symbol
    emc-3
    Official Full Name
    ER membrane protein complex subunit 3
    Primary source
    WormBase:WBGene00013378
    Locus tag
    CELE_Y62E10A.10
    See related
    AllianceGenome:WB:WBGene00013378
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be located in membrane. Predicted to be part of EMC complex. Orthologous to human EMC3 (ER membrane protein complex subunit 3). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See emc-3 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    3
    Sequence:
    Chromosome: IV; NC_003282.8 (13380385..13381923, complement)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene Ribonuclease P protein subunit p20 Neighboring gene Protein kish Neighboring gene NADPH:adrenodoxin oxidoreductase, mitochondrial Neighboring gene Phosducin domain-containing protein;Phosducin thioredoxin-like domain-containing protein Neighboring gene Ras-related protein Rab-10 Neighboring gene Tim44-like domain-containing protein Neighboring gene Mediator complex subunit 9 Neighboring gene Guanine nucleotide exchange factor MSS4

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003282.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A modified TurboID approach identifies tissue-specific centriolar components in C. elegans. Holzer E, et al. PLoS Genet, 2022 Apr. PMID 35442950, Free PMC Article
    2. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
    3. A map of the interactome network of the metazoan C. elegans. Li S, et al. Science, 2004 Jan 23. PMID 14704431, Free PMC Article
    4. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article
    5. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Component Evidence Code Pubs
    part_of EMC complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    ER membrane protein complex subunit 3
    NP_502575.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      13380385..13381923 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_070174.8 → NP_502575.1  ER membrane protein complex subunit 3 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_502575.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9U1X6
      Conserved Domains (1) summary
      pfam01956
      Location:3 → 188
      DUF106; Integral membrane protein DUF106
    Nucleotide Protein
    Heading Accession and Version

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