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    try-4 Peptidase S1 domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 185148, updated on 9-Dec-2024

    Summary

    Official Symbol
    try-4
    Official Full Name
    Peptidase S1 domain-containing protein
    Primary source
    WormBase:WBGene00006622
    Locus tag
    CELE_F31D4.6
    See related
    AllianceGenome:WB:WBGene00006622
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable serine-type endopeptidase activity. Predicted to be involved in innate immune response. Predicted to be active in extracellular space. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See try-4 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    6
    Sequence:
    Chromosome: V; NC_003283.11 (20858727..20861153, complement)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene peptidylprolyl isomerase Neighboring gene C-type lectin domain-containing protein Neighboring gene NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 Neighboring gene Pleckstrin homology domain-containing family D member 1 Neighboring gene Potassium channel domain-containing protein Neighboring gene MATH domain-containing protein

    General gene information

    Markers

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables serine-type endopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in innate immune response IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in extracellular space IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    Peptidase S1 domain-containing protein
    NP_508030.4
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      20858727..20861153 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_075629.6NP_508030.4  Peptidase S1 domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_508030.4

      Status: REVIEWED

      UniProtKB/TrEMBL
      O45421
      Conserved Domains (1) summary
      cd00190
      Location:51318
      Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...