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    clp-9 Calpain catalytic domain-containing protein;RanBP2-type domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 266916, updated on 9-Dec-2024

    Summary

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    Official Symbol
    clp-9
    Official Full Name
    Calpain catalytic domain-containing protein;RanBP2-type domain-containing protein
    Primary source
    WormBase:WBGene00011705
    Locus tag
    CELE_T11A5.6
    See related
    AllianceGenome:WB:WBGene00011705
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable calcium-dependent cysteine-type endopeptidase activity. Predicted to be involved in proteolysis. Predicted to be active in cytoplasm. Is expressed in hypodermis; nervous system; pharynx; reproductive system; and tail. Orthologous to human CAPN15 (calpain 15). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See clp-9 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    11
    Sequence:
    Chromosome: V; NC_003283.11 (9882034..9885968, complement)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene G_PROTEIN_RECEP_F1_2 domain-containing protein Neighboring gene SKN-1 Dependent Zygotic transcript Neighboring gene ncRNA Neighboring gene G-protein coupled receptors family 1 profile domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. SOLH, a human homologue of the Drosophila melanogaster small optic lobes gene is a member of the calpain and zinc-finger gene families and maps to human chromosome 16p13.3 near CATM (cataract with microphthalmia). Kamei M, et al. Genomics, 1998 Jul 15. PMID 9722942
    2. Empirically controlled mapping of the Caenorhabditis elegans protein-protein interactome network. Simonis N, et al. Nat Methods, 2009 Jan. PMID 19123269, Free PMC Article
    3. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    4. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
    5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables calcium-dependent cysteine-type endopeptidase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables calcium-dependent cysteine-type endopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables cysteine-type peptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in proteolysis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Calpain catalytic domain-containing protein;RanBP2-type domain-containing protein
    NP_001256150.1
    • Confirmed by transcript evidence
    NP_001256152.1
    • Confirmed by transcript evidence
    NP_001370282.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      9882034..9885968 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001383377.1 → NP_001370282.1  Calpain catalytic domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      F1LIM7
      Conserved Domains (1) summary
      smart00230
      Location:21 → 351
      CysPc; Calpain-like thiol protease family

    2. NM_001269221.3 → NP_001256150.1  Calpain catalytic domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001256150.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      G5EEZ6
      Conserved Domains (1) summary
      smart00230
      Location:123 → 453
      CysPc; Calpain-like thiol protease family

    3. NM_001269223.2 → NP_001256152.1  RanBP2-type domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001256152.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      G5ED12
    Nucleotide Protein
    Heading Accession and Version

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