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    vha-19 V-type proton ATPase subunit S1 [ Caenorhabditis elegans ]

    Gene ID: 177103, updated on 9-Dec-2024

    Summary

    Official Symbol
    vha-19
    Official Full Name
    V-type proton ATPase subunit S1
    Primary source
    WormBase:WBGene00021952
    Locus tag
    CELE_Y55H10A.1
    See related
    AllianceGenome:WB:WBGene00021952
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable ATPase activator activity. Involved in intracellular water homeostasis; positive regulation of oocyte development; and positive regulation of protein targeting to membrane. Located in membrane raft. Is expressed in excretory cell; hypodermis; intestine; pharynx; and vulva. Human ortholog(s) of this gene implicated in immunodeficiency 47. Orthologous to human ATP6AP1 (ATPase H+ transporting accessory protein 1) and ATP6AP1L (ATPase H+ transporting accessory protein 1 like (pseudogene)). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See vha-19 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    6
    Sequence:
    Chromosome: IV; NC_003282.8 (3369197..3373485)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene G_PROTEIN_RECEP_F1_2 domain-containing protein Neighboring gene ncRNA Neighboring gene G-protein coupled receptors family 1 profile domain-containing protein Neighboring gene ubiquitinyl hydrolase 1 Neighboring gene SRR1 domain-containing protein;Yippee domain-containing protein Neighboring gene Protein yippee-like B0546.4

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General protein information

    Preferred Names
    V-type proton ATPase subunit S1
    NP_500332.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      3369197..3373485
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_067931.5NP_500332.1  V-type proton ATPase subunit S1 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_500332.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9TYW1
      Conserved Domains (1) summary
      pfam05827
      Location:16430
      ATP-synt_S1; Vacuolar ATP synthase subunit S1 (ATP6S1)