C07D8.6 NADP-dependent oxidoreductase domain-containing protein [Caenorhabditis elegans] - Gene

Summary

Official Symbol: C07D8.6
Official Full Name: NADP-dependent oxidoreductase domain-containing protein
Primary source: WormBase:WBGene00015565
Locus tag: CELE_C07D8.6
See related: AllianceGenome:WB:WBGene00015565
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable aldose reductase (NADPH) activity. Predicted to be involved in small molecule metabolic process. Predicted to be active in cytosol. Is expressed in germ line. Human ortholog(s) of this gene implicated in arteriosclerosis; cataract; diabetic neuropathy; diabetic retinopathy; and type 2 diabetes mellitus. Orthologous to human AKR1B1 (aldo-keto reductase family 1 member B); AKR1B10 (aldo-keto reductase family 1 member B10); and AKR1B15 (aldo-keto reductase family 1 member B15). [provided by Alliance of Genome Resources, Dec 2024]
NEW: Try the new Gene table
Try the new Transcript table

Chromosome X - NC_003284.9 Genomic Context describing neighboring genes

Go to nucleotide: Graphics FASTA GenBank

Submit: New GeneRIF Correction

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables aldose reductase (NADPH) activity	IBA Inferred from Biological aspect of Ancestor more info
enables oxidoreductase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in small molecule metabolic process	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in cytosol	IBA Inferred from Biological aspect of Ancestor more info

NP_509242.1

NEW Try the new Transcript table

The following sections contain reference sequences that belong to a specific genome build. Explain