ech-2 Enoyl-CoA hydratase domain-containing protein 3, mitochondrial [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: ech-2
Official Full Name: Enoyl-CoA hydratase domain-containing protein 3, mitochondrial
Primary source: WormBase:WBGene00001151
Locus tag: CELE_F38H4.8
See related: AllianceGenome:WB:WBGene00001151
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable hydro-lyase activity. Predicted to be active in mitochondrion. Orthologous to human ECHDC3 (enoyl-CoA hydratase domain containing 3). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See ech-2 in Genome Data Viewer

Location:: chromosome: IV

Exon count:: 6

Sequence:: Chromosome: IV; NC_003282.8 (11854993..11856351, complement)

Chromosome IV - NC_003282.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003282.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

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Pathways from PubChem

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

F38H4.8 (e-PCR)
- UniSTS:310206

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables hydro-lyase activity	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in mitochondrion	IBA Inferred from Biological aspect of Ancestor more info
located_in mitochondrion	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: Enoyl-CoA hydratase domain-containing protein 3, mitochondrial

NP_001255592.1

Confirmed by transcript evidence

NP_001255593.1

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003282.8 Reference assembly

Range

11854993..11856351 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_001268664.3 → NP_001255593.1 Enoyl-CoA hydratase domain-containing protein 3, mitochondrial [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_001255593.1

Status: REVIEWED

UniProtKB/TrEMBL

D1MN80

Conserved Domains (1) summary

cl23717
Location:17 → 284

crotonase-like; Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. ...
NM_001268663.3 → NP_001255592.1 Enoyl-CoA hydratase domain-containing protein 3, mitochondrial [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_001255592.1

Status: REVIEWED

UniProtKB/TrEMBL

Q20184

Conserved Domains (1) summary

cl23717
Location:17 → 270

crotonase-like; Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. ...