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    T28B8.4 Proteasome activator complex subunit 4 [ Caenorhabditis elegans ]

    Gene ID: 13181077, updated on 9-Dec-2024

    Summary

    Official Symbol
    T28B8.4
    Official Full Name
    Proteasome activator complex subunit 4
    Primary source
    WormBase:WBGene00012115
    Locus tag
    CELE_T28B8.4
    See related
    AllianceGenome:WB:WBGene00012115
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable lysine-acetylated histone binding activity; peptidase activator activity; and proteasome binding activity. Predicted to be involved in proteasomal ubiquitin-independent protein catabolic process. Predicted to be part of proteasome complex. Predicted to be active in cytosol and nucleus. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See T28B8.4 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    23
    Sequence:
    Chromosome: I; NC_003279.8 (8160468..8168711)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene DUF3437 domain-containing protein;Proteasome activator complex subunit 4 C-terminal domain-containing protein Neighboring gene Secreted protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene pseudo Neighboring gene Calmodulin-binding domain-containing protein Neighboring gene Serpentine Receptor, class Z

    Interactions

    General gene information

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables lysine-acetylated histone binding  
    enables lysine-acetylated histone binding  
    enables peptidase activator activity  
    enables peptidase activator activity  
    enables proteasome binding  
    enables proteasome binding  
    Component Evidence Code Pubs
    is_active_in cytosol  
    is_active_in nucleus  
    part_of proteasome complex  

    General protein information

    Preferred Names
    Proteasome activator complex subunit 4
    NP_001263461.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      8160468..8168711
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001276532.4NP_001263461.1  Proteasome activator complex subunit 4 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001263461.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      K7ZUR1
      Conserved Domains (2) summary
      pfam11919
      Location:17891873
      DUF3437; Domain of unknown function (DUF3437)
      pfam16507
      Location:334860
      BLM10_mid; Proteasome-substrate-size regulator, mid region
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