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    ccch-1 C3H1-type domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 179584, updated on 9-Dec-2024

    Summary

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    Official Symbol
    ccch-1
    Official Full Name
    C3H1-type domain-containing protein
    Primary source
    WormBase:WBGene00009532
    Locus tag
    CELE_F38B7.1
    See related
    AllianceGenome:WB:WBGene00009532
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable mRNA binding activity and metal ion binding activity. Located in sarcoplasmic reticulum. Is expressed in several structures, including body wall musculature; intestine; neurons; pharynx; and vulval muscle. Orthologous to several human genes including ZFP36 (ZFP36 ring finger protein). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See ccch-1 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    11
    Sequence:
    Chromosome: V; NC_003283.11 (11527831..11541219)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene RNA polymerase II-associated factor 1 homolog Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene CX domain-containing protein Neighboring gene CX domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Alternative splicing regulation during C. elegans development: splicing factors as regulated targets. Barberan-Soler S, et al. PLoS Genet, 2008 Feb 29. PMID 18454200, Free PMC Article
    2. Determining the sub-cellular localization of proteins within Caenorhabditis elegans body wall muscle. Meissner B, et al. PLoS One, 2011. PMID 21611156, Free PMC Article
    3. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    4. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
    5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables mRNA 3'-UTR binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables mRNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in sarcoplasmic reticulum HDA PubMed 

    General protein information

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    Preferred Names
    C3H1-type domain-containing protein
    NP_505926.2
    • Confirmed by transcript evidence
    NP_505927.2
    • Partially confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      11527831..11541219
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_073525.8 → NP_505926.2  C3H1-type domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_505926.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q20155
      Conserved Domains (2) summary
      COG5063
      Location:19 → 263
      CTH1; CCCH-type Zn-finger protein [General function prediction only]
      pfam00642
      Location:237 → 263
      zf-CCCH; Zinc finger C-x8-C-x5-C-x3-H type (and similar)

    2. NM_073526.6 → NP_505927.2  C3H1-type domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_505927.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7YXD9
      Conserved Domains (1) summary
      pfam00642
      Location:196 → 222
      zf-CCCH; Zinc finger C-x8-C-x5-C-x3-H type (and similar)
    Nucleotide Protein
    Heading Accession and Version

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