Bpifb3 BPI fold containing family B, member 3 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Bpifb3provided by RGD
Official Full Name: BPI fold containing family B, member 3provided by RGD
Primary source: RGD:1565613
See related: EnsemblRapid:ENSRNOG00000075637 AllianceGenome:RGD:1565613
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: Rya3; Lplunc3
Summary: Predicted to enable lipid binding activity. Predicted to be located in cytoplasm. Orthologous to human BPIFB3 (BPI fold containing family B member 3). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Low expression observed in reference dataset See more
Orthologs: human mouse all
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Genomic context

Location:: 3q41

Exon count:: 17

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	3	NC_086021.1 (162861234..162875850)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	3	NC_051338.1 (142401068..142415684)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	3	NC_005102.4 (149401890..149416506)

Chromosome 3 - NC_086021.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables lipid binding	IEA Inferred from Electronic Annotation more info
enables odorant binding	NAS Non-traceable Author Statement more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	ISO Inferred from Sequence Orthology more info
located_in cytoplasm	ISS Inferred from Sequence or Structural Similarity more info
located_in extracellular region	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: BPI fold-containing family B member 3

Names: Long palate, lung and nasal epithelium carcinoma associated protein 3; Potential ligand-binding protein RYA3; antimicrobial peptide RYA3; ligand-binding protein RYA3; long palate, lung and nasal epithelium carcinoma-associated protein 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001109208.1 → NP_001102678.1 BPI fold-containing family B member 3 precursor

See identical proteins and their annotated locations for NP_001102678.1

Status: PROVISIONAL

Source sequence(s)

CH474050

UniProtKB/TrEMBL

A6KHX0

Conserved Domains (2) summary

smart00329
Location:259 → 457

BPI2; BPI/LBP/CETP C-terminal domain

cl00188
Location:26 → 235

BPI; BPI/LBP/CETP domain; Bactericidal permeability-increasing protein (BPI) / Lipopolysaccharide-binding protein (LBP) / Cholesteryl ester transfer protein (CETP) domain; binds to and neutralizes lipopolysaccharides from the outer membrane of Gram-negative ...

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

NC_086021.1 Reference GRCr8

Range

162861234..162875850

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_006235352.5 → XP_006235414.1 BPI fold-containing family B member 3 isoform X1

See identical proteins and their annotated locations for XP_006235414.1

UniProtKB/Swiss-Prot

Q05701

Related

ENSRNOP00000093175.2, ENSRNOT00000094034.2

Conserved Domains (2) summary

smart00329
Location:273 → 471

BPI2; BPI/LBP/CETP C-terminal domain

cl00188
Location:30 → 272

BPI; BPI/LBP/CETP domain; Bactericidal permeability-increasing protein (BPI) / Lipopolysaccharide-binding protein (LBP) / Cholesteryl ester transfer protein (CETP) domain; binds to and neutralizes lipopolysaccharides from the outer membrane of Gram-negative ...