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    Gpr152 G protein-coupled receptor 152 [ Mus musculus (house mouse) ]

    Gene ID: 269053, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Gpr152provided by MGI
    Official Full Name
    G protein-coupled receptor 152provided by MGI
    Primary source
    MGI:MGI:2685519
    See related
    Ensembl:ENSMUSG00000044724 AllianceGenome:MGI:2685519
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gm673; A930009H15Rik
    Summary
    Predicted to enable G protein-coupled receptor activity and identical protein binding activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be active in plasma membrane. Is expressed in retina. Orthologous to human GPR152 (G protein-coupled receptor 152). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Low expression observed in reference dataset See more
    Orthologs
    human all
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    Genomic context

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    See Gpr152 in Genome Data Viewer
    Location:
    19 A; 19 3.84 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 19 NC_000085.7 (4189798..4195740)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 19 NC_000085.6 (4139799..4145741)

    Chromosome 19 - NC_000085.7Genomic Context describing neighboring genes Neighboring gene aryl-hydrocarbon receptor-interacting protein Neighboring gene STARR-positive B cell enhancer ABC_E1966 Neighboring gene transmembrane protein 134 Neighboring gene STARR-positive B cell enhancer ABC_E5674 Neighboring gene calcium binding protein 4 Neighboring gene STARR-positive B cell enhancer ABC_E11665 Neighboring gene CapStarr-seq enhancer MGSCv37_chr19:4148564-4148673 Neighboring gene coronin, actin binding protein 1B Neighboring gene CapStarr-seq enhancer MGSCv37_chr19:4155019-4155206 Neighboring gene STARR-positive B cell enhancer ABC_E5675 Neighboring gene protein tyrosine phosphatase receptor type C polypeptide-associated protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Inactivation of the microRNA-183/96/182 cluster results in syndromic retinal degeneration. Lumayag S, et al. Proc Natl Acad Sci U S A, 2013 Feb 5. PMID 23341629, Free PMC Article
    2. Mouse screen reveals multiple new genes underlying mouse and human hearing loss. Ingham NJ, et al. PLoS Biol, 2019 Apr. PMID 30973865, Free PMC Article
    3. High-throughput discovery of novel developmental phenotypes. Dickinson ME, et al. Nature, 2016 Sep 22. PMID 27626380, Free PMC Article
    4. Genetic determinants of micronucleus formation in vivo. Adams DJ, et al. Nature, 2024 Mar. PMID 38355793, Free PMC Article
    5. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article

    See all (15) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 
    • Targeted (2) 

    Pathways from PubChem

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    General gene information

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    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables G protein-coupled receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables G protein-coupled receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables identical protein binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables identical protein binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    Process Evidence Code Pubs
    involved_in G protein-coupled receptor signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in G protein-coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    probable G-protein coupled receptor 152
    Names
    putative G-protein coupled receptor

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_206973.2 → NP_996856.1  probable G-protein coupled receptor 152

      See identical proteins and their annotated locations for NP_996856.1

      Status: PROVISIONAL

      Source sequence(s)
      BC099681
      Consensus CDS
      CCDS29417.1
      UniProtKB/Swiss-Prot
      Q499X3, Q8BXS7
      Related
      ENSMUSP00000094062.4, ENSMUST00000096338.5
      Conserved Domains (2) summary
      pfam00001
      Location:76 → 295
      7tm_1; 7 transmembrane receptor (rhodopsin family)
      pfam14650
      Location:403 → 451
      FAM75; FAM75 family

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000085.7 Reference GRCm39 C57BL/6J

      Range
      4189798..4195740
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8BXS7.1 GenPept UniProtKB/Swiss-Prot:Q8BXS7

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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