U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    metallo-dependent hydrolase superfamily protein [ Saccharomyces cerevisiae S288C ]

    Gene ID: 853375, updated on 2-Nov-2024

    Summary

    Go to the top of the page Help
    Official Full Name
    metallo-dependent hydrolase superfamily protein
    Primary source
    SGD:S000003606
    Locus tag
    YJL070C
    See related
    AllianceGenome:SGD:S000003606; FungiDB:YJL070C; VEuPathDB:YJL070C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Located in mitochondrion. [provided by Alliance of Genome Resources, Nov 2024]
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    Location:
    chromosome: X
    Exon count:
    1
    Sequence:
    Chromosome: X; NC_001142.9 (307971..310637, complement)

    Chromosome X - NC_001142.9Genomic Context describing neighboring genes Neighboring gene DNA replication protein PSF2 Neighboring gene acetyl-CoA:L-glutamate N-acetyltransferase Neighboring gene Utp18p Neighboring gene S-formylglutathione hydrolase

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_001142.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Phenotypic consequences of purine nucleotide imbalance in Saccharomyces cerevisiae. Saint-Marc C, et al. Genetics, 2009 Oct. PMID 19635936, Free PMC Article
    2. Disruption of six ORFs on Saccharomyces cerevisiae chromosome X: the YJL069c gene of unknown function is essential to cell viability. Vandenbol M, et al. Yeast, 1999 Sep 30. PMID 10509023
    3. Exposing the fitness contribution of duplicated genes. DeLuna A, et al. Nat Genet, 2008 May. PMID 18408719
    4. Mapping the functional yeast ABC transporter interactome. Snider J, et al. Nat Chem Biol, 2013 Sep. PMID 23831759, Free PMC Article
    5. Functional profiling of the Saccharomyces cerevisiae genome. Giaever G, et al. Nature, 2002 Jul 25. PMID 12140549

    See all (31) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Data show that verexpression of YJL070c instead mimics a loss of AMPD function.
      Title: Phenotypic consequences of purine nucleotide imbalance in Saccharomyces cerevisiae.
    Submit: New GeneRIF Correction

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm HDA PubMed 
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in mitochondrion HDA PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    metallo-dependent hydrolase superfamily protein
    NP_012465.3
    • Putative metallo-dependent hydrolase superfamily protein; similar to AMP deaminases but lacks key catalytic residues and does not rescue purine nucleotide metabolic defect of quadruple aah1 ade8 amd1 his1 mutant; may regulate purine nucleotide homeostasis as overexpression in an AMD1 strain grown in adenine results in greatly reduced GDP and GTP intracellular levels; not an essential gene; YJL070C has a paralog, YBR284W, that arose from the whole genome duplication

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001142.9 Reference assembly

      Range
      307971..310637 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001181503.3 → NP_012465.3  TPA: metallo-dependent hydrolase superfamily protein [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_012465.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VWB3, P40361
      UniProtKB/TrEMBL
      A6ZPQ3, B3LQ41, C7GR43, C8ZB90, N1P1A2
      Conserved Domains (1) summary
      COG1816
      Location:405 → 832
      Add; Adenosine deaminase [Nucleotide transport and metabolism]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P40361.1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.