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    [ Saccharomyces cerevisiae S288C ]

    Gene ID: 856730, updated on 9-Dec-2024

    Summary

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    Primary source
    SGD:S000006550
    Locus tag
    YNCE0012W
    See related
    AllianceGenome:SGD:S000006550
    Gene type
    tRNA
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Predicted to enable triplet codon-amino acid adaptor activity. Predicted to be involved in translational elongation. Predicted to be located in cytosol. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    Location:
    chromosome: V
    Sequence:
    Chromosome: V; NC_001137.3 (177099..177170)

    Chromosome V - NC_001137.3Genomic Context describing neighboring genes Neighboring gene bifunctional 4-hydroxy-4-methyl-2-oxoglutarate aldolase/oxaloacetate decarboxylase Neighboring gene GPI-anchored mannoprotein Neighboring gene proteasome core particle subunit beta 4 Neighboring gene DEAH-box ATP-dependent RNA helicase PRP22

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001137.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Elongator complex influences telomeric gene silencing and DNA damage response by its role in wobble uridine tRNA modification. Chen C, et al. PLoS Genet, 2011 Sep. PMID 21912530, Free PMC Article
    2. A conserved modified wobble nucleoside (mcm5s2U) in lysyl-tRNA is required for viability in yeast. Björk GR, et al. RNA, 2007 Aug. PMID 17592039, Free PMC Article
    3. A genome-wide screen identifies genes required for formation of the wobble nucleoside 5-methoxycarbonylmethyl-2-thiouridine in Saccharomyces cerevisiae. Huang B, et al. RNA, 2008 Oct. PMID 18755837, Free PMC Article
    4. tRNA genes and retroelements in the yeast genome. Hani J, et al. Nucleic Acids Res, 1998 Feb 1. PMID 9443958, Free PMC Article
    5. Transfer RNA gene redundancy and translational selection in Saccharomyces cerevisiae. Percudani R, et al. J Mol Biol, 1997 May 2. PMID 9159473

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    • Glutamate tRNA (tRNA-Glu), predicted by tRNAscan-SE analysis; thiolation of uridine at wobble position (34) requires Ncs6p; target of K. lactis zymocin

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables triplet codon-amino acid adaptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables triplet codon-amino acid adaptor activity ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in translational elongation IC
    Inferred by Curator
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol IC
    Inferred by Curator
    more info
    		 PubMed 

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