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    OCA6 protein-tyrosine-phosphatase [ Saccharomyces cerevisiae S288C ]

    Gene ID: 851639, updated on 9-Dec-2024

    Summary

    Official Symbol
    OCA6
    Official Full Name
    protein-tyrosine-phosphatase
    Primary source
    SGD:S000002474
    Locus tag
    YDR067C
    See related
    AllianceGenome:SGD:S000002474; FungiDB:YDR067C; VEuPathDB:YDR067C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Predicted to enable phosphatase activity. Predicted to be involved in protein dephosphorylation. Located in cytoplasm. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See OCA6 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    1
    Sequence:
    Chromosome: IV; NC_001136.10 (582791..583465, complement)

    Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene Rrg1p Neighboring gene putative protein-serine/threonine phosphatase Neighboring gene Dos2p Neighboring gene ubiquitin-specific protease DOA4

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables histone H2AXY142 phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables molecular_function ND
    No biological Data available
    more info
     
    enables non-membrane spanning protein tyrosine phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables phosphatase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables phosphoprotein phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein tyrosine phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein tyrosine phosphatase activity, metal-dependent IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
     
    involved_in chromatin remodeling IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm HDA PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    protein-tyrosine-phosphatase
    NP_010352.1
    • Cytoplasmic protein required for replication of Brome mosaic virus; S. cerevisiae is a model system for studying positive-strand RNA virus replication; null mutation confers sensitivity to tunicamycin and DTT

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001136.10 Reference assembly

      Range
      582791..583465 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001180375.1NP_010352.1  TPA: protein-tyrosine-phosphatase [Saccharomyces cerevisiae S288C]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VS53, Q12454, Q6Q559
      UniProtKB/TrEMBL
      A6ZY32, B3LGK3, C7GVR9, C8Z4Y5, G2WAH1, N1P4L8
      Conserved Domains (1) summary
      cd17663
      Location:4181
      PFA-DSP_Oca6; atypical dual specificity phosphatases similar to oxidant-induced cell-cycle arrest protein 6